NCT07181993

Brief Summary

Purpose: This study aims to validate the medication entries in the PRISCUS list-a German expert-based compilation of potentially inappropriate medications for older adults-and to identify additional medications that may pose a fall risk but are not yet included. Study Design: This is a retrospective observational study uses electronic health record data from a German research hospital. It includes over 900,000 patient records from multiple departments with a high incidence of falls, covering the period from 2016 to 2022. Statistical analyses, including chi-square tests and propensity score matching, will be employed to evaluate the relationship between medications and fall events.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
932,912

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2024

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2024

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2024

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

September 9, 2025

Completed
10 days until next milestone

First Posted

Study publicly available on registry

September 19, 2025

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2025

Completed
Last Updated

September 19, 2025

Status Verified

September 1, 2025

Enrollment Period

Same day

First QC Date

September 9, 2025

Last Update Submit

September 16, 2025

Conditions

Fall Injury

Outcome Measures

Primary Outcomes (1)

  • Number of Participants with Fall Incidents

    In-patients that have experienced a fall within the hospital premises

    From January 2016 to October 2022

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with patient records between 2016-2022 across 20 clinical departments with highest fall incidence

You may qualify if:

  • All patients across 20 clinical departments with highest fall incidence

You may not qualify if:

  • Age \< 18yrs

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Institute for Medical Informatics | Charité Universitätsmedizin Berlin

Berlin, State of Berlin, 10115, Germany

Location

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof. Dr. rer. pol.

Study Record Dates

First Submitted

September 9, 2025

First Posted

September 19, 2025

Study Start

September 1, 2024

Primary Completion

September 1, 2024

Study Completion

December 31, 2025

Last Updated

September 19, 2025

Record last verified: 2025-09

Locations

DE(1)