Correlation Between the Midpalatal Suture Maturity and the Maxillary Third Molar Mineralization: a CBCT Study

NCT07181707 | Completed

• 1 other identifier: 2025PI009
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

Assessing the maturation of the mid-palatal suture is an essential criterion for orthodontic decision-making. However, from a CBCT according to Angelieri's classification , it remains difficult for the practitioner's untrained eye. As profile teleradiographs are almost routinely performed in orthodontic check-ups, numerous studies have looked for a correlation between the stage of maturation of the palatal suture and that of the cervical vertebrae. Some have also looked for a link with mineralization of mandibular third or second molars according to Demirjian's classification. These techniques would provide a reliable and reproducible method without the use of CBCT. In our study, the investigators will be looking for a correlation with mineralization of the maxillary third molar according to Nolla's classification. The latter has become common in practice and easy to apply on an orthopantomogram. This would simplify decision-making without the need for a CBCT, but by using the orthopantomogram which is already routinely performed during the assessment.

Conditions

Maturation of the Midpalatal Suture and Maxillary Third Molar Mineralization in Healthy Individuals

Keywords

Molar, third; Cone Beam Computed Tomography; cranial suture; tooth calcification

Outcome Measures

Primary Outcomes (2)

• Maturation stages of the midpalatal suture

  Stages according to Angelieri et al.

  One day

• Third molar calcification

  Calcification's stages of the third left molar maxillary (from 0 to 10) according to Nolla.

  One day

Study Arms (4)

Patient aged under 14 years

Patients aged under 14 years.

Patients aged between 14 and 18 years.

Patients aged between 14 and 18 years.

Patients aged between 19 and 25 years.

Patients aged between 19 and 25 years.

Patients aged over 25 years.

Patients aged over 25 years.

Eligibility Criteria

• Age: 9 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Odontology department's patients

You may qualify if:

• No previous orthodontic or orthopedic treatment
• At least the maxillary third left molar
• No skeletal disability

You may not qualify if:

• Previous maxillofacial trauma
• Dentofacial deformities
• Endocrinological pathologies with implications for maxillofacial growth • - Syndromes
• History of maxillofacial or orthognathic surgery
• History of orthodontic treatment
• Incomplete data or incomplete CBCT
• Maxillary third left molar fracture/cavity/other deterioratedation

Sponsors & Collaborators

• Central Hospital, Nancy, France: lead

Study Sites (1)

Caroline Bertazzon

Nancy, France, 54000, France

Location

Study Officials

• Bart VANDE VANNET, PhD

  Central Hospital, Nancy, France

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: September 12, 2025
• First Posted: September 18, 2025
• Study Start: January 1, 2026
• Primary Completion: March 26, 2026
• Study Completion: March 26, 2026
• Last Updated: April 30, 2026

Record last verified: 2026-04

Locations

FR (1)