Early Prediction and Diagnosis of Acute Kidney Injury

NCT07181174 | Enrolling By Invitation DMC FDA Device

• 1 other identifier: 1016/11/24
• Study Type: observational
• Target: 45
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to estimate the accuracy of renal resistive index in early diagnosis and prediction of acute kidney injury in patients with hemorrhagic stroke. the main questions it aims to answer are :

• Early detection of acute kidney injury in patient with hemorrhagic stroke .
• Decrease morbidity and mortality rate in patients with hemorrhagic stroke .

Conditions

Early Diagnosis of Acute Kidney Injury

Outcome Measures

Primary Outcomes (1)

• Early detection of acute kidney injury in patient with hemorrhagic stroke

  within 2 days and 1 week

Interventions

Ultrasonographic examination and doppler ultrasonography will be performed using a convex transducer. DEVICE

-Renal Resistive Index Measurement Method: Ultrasonographic examination and doppler ultrasonography will be performed using a convex transducer. First, the kidney is localised in the flanks with conventional B-mode ultrasonography, after which, color doppler images are acquired. The interlobar arteries were visualised, with the wavelength obtained by creating a 90-degree right-angle with the interlobar artery using a power doppler. After the manual determination of the peak systolic and end-diastolic velocities \* RRI will be calculated by the device using the formula: RRI = (peak systolic velocity - end-diastolic velocity) / (peak systolic velocity). RRI will be measured three times for each kidney and averaged

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

patients with hemorrhagic stroke

You may qualify if:

• All patients with hemorrhagic stroke presented to Aswan university hospital that will be fulfilled the following characters:
• Age \>18 years.
• Both sex.
• Cases of spontaneous onset

You may not qualify if:

• Age \< 18
• Patients with traumatic hemorrhagic stroke.
• Patients with brain tumors.
• Patients with congenital anomalies of cerebral vessels e.g. AVM (arteriovenous malformation) and cerebral aneurysm.
• Patients with history of any renal diseases

Sponsors & Collaborators

• Aswan University: lead

Study Sites (1)

Aswan university hospitals- Neurology Department

Aswān, 1240801, Egypt

Location

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident of neuropsychiatry department

Study Record Dates

• First Submitted: September 12, 2025
• First Posted: September 18, 2025
• Study Start: December 1, 2024
• Primary Completion: December 1, 2025
• Study Completion: January 1, 2026
• Last Updated: September 18, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)