Surgical Correction of V Pattern Intermittent Exotropia Without Inferior Oblique Muscle Overaction

NCT07180199 | Completed

• 1 other identifier: 36264MS244/7/23
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

Evaluation of the results of surgical correction of V pattern intermittent exotropia without inferior oblique muscle overaction by either performing bilateral lateral rectus recession (BLR) alone or performing bilateral lateral rectus recession asssosiated with upward transposition of lateral rectus muscle insertion

Conditions

Surgical Correction; V Pattern; Intermittent Exotropia; Inferior Oblique Muscle; Overaction

Outcome Measures

Primary Outcomes (1)

• Angle of Ocular Deviation

  The degree of ocular misalignment was measured using prism cover test at near and distance fixation. Successful outcome was defined as residual deviation ≤10 prism diopters.

  6 months postoperatively

Secondary Outcomes (1)

• Postoperative Complications

  6 months postoperatively

Study Arms (2)

Bilateral Lateral Rectus Recession (BLR Recession)

EXPERIMENTAL

Participants underwent bilateral lateral rectus recession procedure alone for correction of large-angle exotropia.

Procedure: Bilateral Lateral Rectus Recession (BLR Recession)

Bilateral Lateral Rectus Recession with Upward Transposition

EXPERIMENTAL

Participants underwent bilateral lateral rectus recession combined with upward transposition of the muscle insertion to enhance alignment in cases of large-angle exotropia.

Procedure: Bilateral Lateral Rectus Recession with Upward Transposition

Interventions

Bilateral Lateral Rectus Recession (BLR Recession) PROCEDURE

This procedure involved recession of both lateral rectus muscles to reduce large-angle exotropia.

Bilateral Lateral Rectus Recession (BLR Recession)

Bilateral Lateral Rectus Recession with Upward Transposition PROCEDURE

This procedure involved bilateral lateral rectus recession combined with upward transposition of the insertion to enhance ocular alignment in patients with large-angle exotropia.

Bilateral Lateral Rectus Recession with Upward Transposition

Eligibility Criteria

• Age: 5 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with V pattern intermittent exotropia (XT increasing by \>10Δ in upgaze compared with Downgaze).
• No or minimal inferior oblique overaction on both sides (+1)
• Minimum follow-up period of 6 months after surgical correction of strabismus

You may not qualify if:

• Structural eye pathology.
• Significant neurodevelopmental delay.
• ntermittent exotropia without V pattern.
• Superior oblique under action.
• Duane syndrome.
• Less than 6 months follow up.

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Tanta University

Tanta, El-Gharbia Governorate, Egypt, 31527, Egypt

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident at Ophthalmology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.

Study Record Dates

• First Submitted: September 11, 2025
• First Posted: September 18, 2025
• Study Start: August 30, 2023
• Primary Completion: August 30, 2024
• Study Completion: August 30, 2024
• Last Updated: September 18, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author

Locations

EG (1)