Laminoplasty Versus Laminectomy With Lateral Mass Fixation in Management of Degenerative Cervical Canal Stenosis

NCT07177651 | Not Yet Recruiting

• 1 other identifier: Posterior cervical approaches
• Study Type: interventional
• Target: 2
• Locations: 0 countries
• Sites: N/A

Brief Summary

Cervical canal stenosis (CCS) is a condition characterized by the narrowing of the spinal canal in the cervical spine, leading to compression of the spinal cord and nerve roots. This can result in a variety of neurological deficits, including myelopathy, radiculopathy, and motor dysfunction. The primary goal of treatment is to relieve neural compression and improve or preserve neurological function. Surgical decompression, such as laminoplasty, is a common procedure to treat this condition, as it decompresses the spinal canal to relieve pressure on the spinal cord. Laminectomy with lateral mass fixation is another option of management.

Conditions

Cervical Stenosis; Degenerative Cervical Spinal Stenosis

Keywords

Laminoplasty; Lateral mass fixation

Outcome Measures

Primary Outcomes (1)

• Change in modified Japanese Orthopaedic Association (mJOA) score from baseline to 6 months (neurological function; range 0-17; higher = better function)

  Neurological outcome will be assessed using the modified Japanese Orthopaedic Association (mJOA) score, which evaluates motor and sensory function of the upper and lower extremities, as well as bladder function. Scores range from 0-17, with higher scores indicating better neurological function. Assessments will be performed at baseline (pre-operative), and at 6 months postoperatively by a blinded clinician.

  Baseline and 6 months postoperatively

Secondary Outcomes (2)

• Complication rate within 90 days postoperatively

  Within 90 days postoperatively

• Length of hospital stay (days)

  Perioperative period

Study Arms (2)

Laminoplasty

EXPERIMENTAL

Procedure: Laminoplasty

Laminectomy with lateral mass fixation

EXPERIMENTAL

Procedure: Laminectomy with lateral mass fixation

Interventions

Laminoplasty PROCEDURE

Is a posterior approach that involves the surgical widening of the spinal canal by reshaping or repositioning the lamina. However, some patients with cervical stenosis

Laminoplasty

Laminectomy with lateral mass fixation PROCEDURE

Posterior cervical decompression with lateral mass screw insertion

Laminectomy with lateral mass fixation

Eligibility Criteria

• Age: 40 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients aged 40 ≥ years with clinically significant cervical canal stenosis (based on imaging and neurological symptoms).
• Surgical indication for cervical decompression.
• Adequate follow up data (minimum 1 year).
• Patients fit for surgery.

You may not qualify if:

• Patients unfit for surgery or contraindication to general anaesthesia.
• Congenital deformities or significant spinal deformities unrelated to stenosis.
• Patients with cervical kyphosis, active infection or known allergy to titanium.
• Previous cervical spine surgery.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (1)

• https://www.asianspinejournal.org/journal/view.php?doi=10.4184%2Fasj.2016.10.3.536

  RESULT

Related Links

• Related Info

MeSH Terms

Interventions

Laminoplasty; Laminectomy

Intervention Hierarchy (Ancestors)

Orthopedic Procedures; Therapeutics; Neurosurgical Procedures; Surgical Procedures, Operative; Decompression, Surgical

Study Officials

• Mahmoud Hassan Ragab

  Assiut University hospital, neurosurgery department

  STUDY DIRECTOR

• Abdel Hakeem Abdel Sattar

  Assiut University, neurosurgery department

  STUDY DIRECTOR

Central Study Contacts

Fahd Abdel sabour Ahmed Fahd Abdel Sabour Ahmed, Master degree in neurosurgery

CONTACT

00201029522851; Dfahd81@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator, specialist , neurosurgery department

Study Record Dates

• First Submitted: July 2, 2025
• First Posted: September 17, 2025
• Study Start: October 4, 2025
• Primary Completion: May 1, 2026
• Study Completion (Estimated): March 1, 2027
• Last Updated: September 17, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share