Pontic Shield and Mineralized Plasmatic Matrix for Ridge Preservation

NCT07171879 | Completed

• 1 other identifier: R.25.09.22
• Study Type: interventional
• Target: 56
• Locations: 1 country
• Sites: 1

Brief Summary

This study is testing new methods to preserve the jawbone and gum tissue after removing a damaged front tooth. Normally, when a tooth is taken out, the bone and gums in that area shrink, which can make future dental treatment more difficult and affect appearance. A technique called Partial Extraction Therapy (Pontic Shield Technique) keeps part of the tooth root in place to help maintain the natural shape of the bone and gums. Another method, called Mineralized Plasmatic Matrix (MPM), uses a patient's own blood mixed with bone particles to support healing. In this randomized clinical trial, 56 patients were assigned to one of four groups: Group I: Tooth extraction only Group II: Tooth extraction with MPM grafting Group III: Pontic shield technique alone Group IV: Pontic shield technique with MPM grafting The main outcome measured was the amount of bone width preserved, using 3D X-rays (CBCT). Other outcomes included bone height and soft-tissue healing over 4 months. This research will help determine whether the pontic shield technique, with or without MPM, provides better preservation of bone and gum tissue compared to tooth extraction alone.

Conditions

Alveolar Ridge Preservation

Keywords

Partial extraction therapy; Pontic shield; Mineralized plasmatic matrix (MPM); Socket preservation; Wound healing index

Outcome Measures

Primary Outcomes (1)

• Alveolar Ridge Width Change

  Mean changes in alveolar ridge width measured at standardized reference points on cone-beam computed tomography (CBCT) Unit of Measure: millimeters (mm)

  Baseline (pre- or immediate post-extraction) to 4 months.

Secondary Outcomes (2)

• Buccal and Palatal Bone Height Change

  Baseline to 4 months.

• Soft-Tissue Healing (Wound Healing Index, WHI)

  1 week and 4 months post-extraction.

Study Arms (4)

Extraction Only

ACTIVE COMPARATOR

Patients receive total tooth extraction in the esthetic maxillary zone without any adjunctive grafting.

Procedure: Tooth Extraction only

Extraction + MPM

ACTIVE COMPARATOR

Patients receive total tooth extraction in the esthetic maxillary zone, followed by grafting with MPM.

Procedure: Extraction + MPM

Pontic Shield Only

ACTIVE COMPARATOR

Patients undergo the pontic shield technique, in which a portion of the buccal root is preserved to maintain ridge contour, without grafting.

Procedure: Pontic Shield Only

Pontic Shield + MPM

ACTIVE COMPARATOR

Patients undergo the pontic shield technique combined with MPM grafting for ridge preservation.

Procedure: Pontic Shield + MPM

Interventions

Tooth Extraction only PROCEDURE

Conventional atraumatic extraction of the non-restorable maxillary tooth in the esthetic zone without socket preservation procedures.

Extraction Only

Extraction + MPM PROCEDURE

Tooth extraction followed by socket grafting using MPM, prepared from autologous blood combined with xenograft bone particles.

Extraction + MPM

Pontic Shield Only PROCEDURE

Partial extraction therapy using the pontic shield technique, in which the buccal root fragment is preserved to maintain ridge contour, without additional grafting.

Pontic Shield Only

Pontic Shield + MPM PROCEDURE

Pontic shield technique combined with grafting using mineralized plasmatic matrix (MPM) for enhanced ridge preservation and healing.

Pontic Shield + MPM

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults (≥18 years).
• Classified as ASA I (healthy) according to the American Society of Anesthesiologists Physical Status Classification.
• Presence of Type 1 extraction sockets (intact buccal bone and soft tissues).
• Adequate oral hygiene.
• Sufficient inter-arch space for prosthetic rehabilitation.
• Willingness to comply with study protocol and follow-up schedule.

You may not qualify if:

• Systemic conditions affecting bone metabolism or wound healing (e.g., uncontrolled diabetes, osteoporosis, immunosuppression).
• History of head and neck radiotherapy or bisphosphonate therapy.
• Acute infection or suppuration at the extraction site.
• Severe periodontal disease.
• Root caries or tooth mobility.
• Buccal bone plate loss due to vertical/horizontal root fractures or advanced periodontitis.

Sponsors & Collaborators

• Soaad Tolba Mohammed Tolba Badawi: lead

Study Sites (1)

Faculty of Dentistry, Mansoura University

Al Mansurah, Dakahlia Governorate, 35511, Egypt

Location

MeSH Terms

Interventions

1-methyl-1-piperidinomethane sulfonate

Study Officials

• Soaad Tolba Badawy, Lecturer, Oral Surgery, MU

  Mansoura University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Lecturer of Oral and Maxillofacial Surgery, Faculty of Dentistry, Mansoura University

Model Details: Participants were randomized to one of four groups: extraction alone, extraction with MPM, pontic shield alone, or pontic shield with MPM.

Study Record Dates

• First Submitted: September 6, 2025
• First Posted: September 15, 2025
• Study Start: September 1, 2024
• Primary Completion: July 1, 2025
• Study Completion: July 1, 2025
• Last Updated: September 17, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)