Research for the Precision Medicine in the Treatment of Inflammatory Bowel Disease

NCT07166588 | Enrolling By Invitation

• 1 other identifier: 2012-115-1183
• Study Type: observational
• Target: 2,000
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to establish an integrated cohort of patients with inflammatory bowel disease (IBD) from Seoul National University Hospital, Seoul National University Boramae Medical Center, and Seoul National University Bundang Hospital. Through this cohort, we seek to develop a prognostic prediction model for IBD patients and a predictive model for therapeutic responses to biologic agents and small molecule therapies.

Conditions

Crohn Disease (CD); Ulcerative Colitis (UC); IBD (Inflammatory Bowel Disease)

Keywords

Ulcerative Colitis; Inflammatory Bowel Disease; Crohn Disease

Outcome Measures

Primary Outcomes (1)

• Prediction model in the patients with inflammatory bowel disease for treatment response

  Development of a prognostic prediction model for patients with inflammatory bowel disease and a predictive model for therapeutic response to biologic agents and small molecule therapies

  From enrollment to the end of treatment at 12 weeks

Eligibility Criteria

• Age: 10 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Subjects with inflammatory bowel disease, including Crohn's disease and ulcerative colitis.

You may qualify if:

• Patients aged 10 years or older who have been newly diagnosed with inflammatory bowel disease or are under follow-up monitoring.

You may not qualify if:

• Patients diagnosed with cancer or with a history of cancer treatment.
• Participation may be restricted at the discretion of the medical team.
• Infants and young children under the age of 10.

Sponsors & Collaborators

• Seoul National University Hospital: lead

Study Sites (1)

Seoul National University Hospital

Seoul, Seoul, 03080, South Korea

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

feces, blood, tissue, RNA

MeSH Terms

Conditions

Crohn Disease; Colitis, Ulcerative; Inflammatory Bowel Diseases

Condition Hierarchy (Ancestors)

Gastroenteritis; Gastrointestinal Diseases; Digestive System Diseases; Intestinal Diseases; Colitis; Colonic Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 72 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: September 3, 2025
• First Posted: September 10, 2025
• Study Start: January 20, 2021
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): December 31, 2028
• Last Updated: September 15, 2025

Record last verified: 2025-09

Locations

KR (1)