Intelligent Accelerated MRI for Pediatric Abdominal Pain

NCT07164651 | Active Not Recruiting DMC

• 2 other identifiers: TJ-IRB20241002782471969
• Study Type: observational
• Target: 150
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to evaluate the effectiveness of an intelligent accelerated MRI technique in children with abdominal pain. The main question it aims to answer is: Does the intelligent accelerated MRI reduce scan time while maintaining diagnostic accuracy in pediatric patients? Participants will: Receive an abdominal MRI scan using the accelerated protocol as part of their clinical evaluation. Have their scan duration and image quality compared to conventional MRI standards.

Conditions

Pediatric Abdominal Pain

Keywords

Pediatric abdominal pain; Intelligent accelerated MRI; Image quality; Diagnostic accuracy; Motion artifacts

Outcome Measures

Primary Outcomes (1)

• Scan Time Reduction with Intelligent Accelerated MRI

  Comparison of total scan time (minutes) for abdominal/pelvic MRI using the intelligent accelerated protocol (ACS-T2WI and TACS-T2WI sequences) versus conventional T2WI sequences, while maintaining diagnostic image quality (assessed by radiologists using a 5-point Likert scale).

  During MRI scan procedure (single time point).

Secondary Outcomes (2)

• Diagnostic Accuracy of Accelerated MRI

  Within 24 hours post-scan.

• Motion Artifact Reduction

  During MRI scan procedure (single time point).

Study Arms (1)

1

Pediatric patients who were undergoing MRE examination for abdominal pain

Other: Accelerated MRI scanning

Interventions

Accelerated MRI scanning OTHER

All patients underwent MRI scans of the abdominal and pelvic regions on the uMR 790 scanner at Tongji Hospital's Optical Valley Campus. The scanning protocol included multiplanar ACS T2WI sequences, TACS T2WI sequences, and conventional T2WI sequences. ACS T2WI sequence: Used for preliminary motion artifact correction. TACS T2WI sequence: Employed for advanced motion artifact correction and provided dynamic images of organ movement. Conventional T2WI sequence: Served as the standard reference for comparison.

1

Eligibility Criteria

• Age: 3 Years - 18 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The study population consists of pediatric patients aged 3-18 years presenting with abdominal pain who have undergone a prior abdominal CT examination as part of their clinical evaluation. Eligible participants must have guardians who voluntarily consent to an additional MRI scan and provide written informed consent.

You may qualify if:

• Children aged 3-18 years presenting with abdominal pain who have undergone abdominal CT examination.
• Children whose guardians voluntarily agree to MRI examination and sign written informed consent.

You may not qualify if:

• Children with contraindications to MRI (e.g., metal implants, severe claustrophobia) or those unable to cooperate with the examination.

Sponsors & Collaborators

• Yaqi Shen，MD，PhD: lead
• United Imaging Healthcare: collaborator

Study Sites (1)

Tongji Hospital

Wuhan, Hubei, 430030, China

Location

Related Publications (12)

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  PMID: 25659265 RESULT

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• Murphy LK, Suskind DL, Qu P, Zhou C, Gashi K, Kawamura JS, Palermo TM; ImproveCareNow Pediatric IBD Learning Health System, as stipulated by ICN. Abdominal Pain After Pediatric Inflammatory Bowel Disease Diagnosis: Results From the ImproveCareNow Network. J Pediatr Gastroenterol Nutr. 2020 Dec;71(6):749-754. doi: 10.1097/MPG.0000000000002933.

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  PMID: 27133248 RESULT

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 3 Months
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: September 2, 2025
• First Posted: September 10, 2025
• Study Start: May 26, 2025
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): December 31, 2027
• Last Updated: September 10, 2025

Record last verified: 2025-09

Locations

CN (1)