Nicotine Replacement Therapy Prescribing and Lung Cancer Screening in Hospitalized Patients

NCT07164404 | Active Not Recruiting DMC

• 1 other identifier: Pro00146588
• Study Type: interventional
• Target: 220
• Locations: 1 country
• Sites: 1

Brief Summary

Investigators are evaluating an EHR-based, non-interruptive alert to increase NRT prescribing in the hospital and at discharge for hospitalized patients. Investigators will investigate two randomized groups of resident physicians to evaluate their prescribing behaviors when the tool is introduced.

Conditions

Tobacco Use Disorder

Outcome Measures

Primary Outcomes (3)

• Nicotine Replacement Therapy (NRT) prescribing rates during hospitalization

  During hospitalization, assessed from admission to discharge (average of 3-7 days)

• Nicotine Replacement Therapy (NRT) prescribing rates at discharge

  During hospitalization, assessed from admission to discharge (average of 3-7 days)

• Rate of referral to outpatient tobacco cessation clinic

  During hospitalization, assessed from admission to discharge (average of 3-7 days)

Study Arms (2)

EHR alert

EXPERIMENTAL

Group will have access to the EHR embedded alert into the admission note template, where it automatically inserts smoking history, prompts NRT prescribing in the hospital, and offers referral to outpatient follow up.

Other: EHR alert

Control

NO INTERVENTION

Routine care, no access to the EHR embedded alert

Interventions

EHR alert OTHER

EHR embedded alert into the admission note template, where it automatically inserts smoking history, prompts NRT prescribing in the hospital, and offers referral to outpatient follow up.

EHR alert

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Hospitalized patients admitted to a General Medicine Service at MUSC Charleston
• Identified as actively smoking tobacco via nursing admission screening
• Admitted by a resident physician participating in the study (as indicated by the H\&P note)

You may not qualify if:

• None
• Resident Physicians:
• Internal medicine resident physicians rotating on the hospitalist service at MUSC Health Charleston
• None

Sponsors & Collaborators

• Medical University of South Carolina: lead
• South Carolina Clinical & Translational Research Institute (SCTR): collaborator

Study Sites (1)

Medical University of South Carolina

Charleston, South Carolina, 29407, United States

Location

MeSH Terms

Conditions

Tobacco Use Disorder

Condition Hierarchy (Ancestors)

Substance-Related Disorders; Chemically-Induced Disorders; Mental Disorders

Study Officials

• Ellen Esposito, MD

  Medical University of South Carolina

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 28, 2025
• First Posted: September 10, 2025
• Study Start: November 17, 2025
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): September 1, 2026
• Last Updated: May 8, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)