NCT07162376

Brief Summary

Physicians often form quick judgments about the risk for serious disease when interacting with patients. Underestimating risk can lead to underuse of diagnostic testing and untreated illness, which can worsen patient outcomes. On the other hand, overestimating risk can lead to overuse of diagnostic testing, which is costly for health systems. To form judgments of risk, physicians should attend to a host of validated factors that are predictive of disease. However, research suggests that physicians may rely on demographic factors-such as race and gender. Physicians' judgments could also be influenced by non-health-related, personal information about their patients (e.g., hobbies, nicknames), which may moderate the impact of demographics on those judgments. The investigators examine these dynamics in the context of heart disease. The History, Electrocardiogram, Age, Risk factors and Troponin (HEART) Score is a validated model that specifies a correspondence between certain risk factors and the likelihood of Major Adverse Cardiac Event (MACE). Importantly, there are substantially different diagnostic tests (e.g., noninvasive stress test versus coronary angiogram) that should be used depending on a patient's MACE likelihood. Specifically, the investigators have three research questions:

  • Research Question 1 (RQ1): How accurate are physicians relative to the benchmarks from the HEART score model?
  • Research Question 2 (RQ2): How do clinically-relevant risk factors (e.g., smoking history), race, gender, and personal information disclosure influence risk judgments?
  • Research Question 3 (RQ3): Does personal information disclosure moderate the effects of race and gender on risk judgments? Note that when the investigators discuss accuracy and error, they are referring to the comparison of physician judgments to the HEART score model benchmarks.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
300

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2025

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 25, 2025

Completed
15 days until next milestone

First Posted

Study publicly available on registry

September 9, 2025

Completed
7 days until next milestone

Study Start

First participant enrolled

September 16, 2025

Completed
10 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 26, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 26, 2025

Completed
Last Updated

January 16, 2026

Status Verified

September 1, 2025

Enrollment Period

10 days

First QC Date

August 25, 2025

Last Update Submit

January 14, 2026

Conditions

Keywords

Major Adverse Cardiac Event (MACE)Physician PerceptionRisk JudgmentHEART ScoreDiagnostic TestingCardiologyPersonal Information

Outcome Measures

Primary Outcomes (1)

  • Absolute Error in Perceived Risk of MACE

    For each patient profile, all participants will be asked about their perceived risk of MACE: What is the likelihood that this patient experiences a major adverse cardiac event in the six weeks following the visit? \[0-100\]. The paradigm uses two levels of risk factors, each associated with a specific risk of MACE range as defined by the HEART score model: low risk factors = 0.9-1.7% (midpoint = 1.3%); and medium risk factors = 12-16.6% (midpoint = 14.3%). To calculate each participant's directional error, the investigators will take the difference between participants' perceived risk of MACE and the midpoint of the risk of MACE range from the HEART score model at each patient's corresponding risk level. The absolute error is calculated by taking the absolute value of the directional error.

    At the time of survey completion, within approximately 2 weeks

Secondary Outcomes (5)

  • Perceived Risk of MACE

    At the time of survey completion, within approximately 2 weeks

  • Directional Error

    At the time of survey completion, within approximately 2 weeks

  • Categorical Error

    At the time of survey completion, within approximately 2 weeks

  • Diagnostic Test Decision

    At the time of survey completion, within approximately 2 weeks

  • Overconfidence

    At the time of survey completion, within approximately 2 weeks

Study Arms (2)

No Personal Information Disclosure

NO INTERVENTION

Participants rate 8 patient profiles of patients with chest pain. The profiles each contain info about the patient's race, gender, and risk factors associated with MACE.

Personal Information Disclosure

EXPERIMENTAL

Participants rate 8 patient profiles of patients with chest pain. The profiles each contain info about the patient's race, gender, and risk factors associated with MACE. Each profile also contains non-health related personal information that the patient has disclosed (e.g., nickname, hobbies).

Behavioral: Personal Information Disclosure

Interventions

Each profile also contains non-health related personal information that the patient has disclosed (e.g., nickname, hobbies).

Personal Information Disclosure

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Emergency medicine physicians
  • Cardiologists
  • Hospitalists (i.e., internists whose practice is primarily in the hospital)
  • If there are duplicate participant IDs in the data, only the first response will be included in the analysis

You may not qualify if:

  • Participants who indicate they are retired
  • Participants who write gibberish in the open-ended items
  • Incomplete responses

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Van Munching Hall

College Park, Maryland, 20742, United States

Location

Study Officials

  • Joseph Reiff, PhD

    University of Maryland Robert H. Smith School of Business

    PRINCIPAL INVESTIGATOR
  • Aneesh Rai, PhD

    University of Maryland Robert H. Smith School of Business

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Model Details: Parallel randomized trial at the physician level.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor of Marketing

Study Record Dates

First Submitted

August 25, 2025

First Posted

September 9, 2025

Study Start

September 16, 2025

Primary Completion

September 26, 2025

Study Completion

September 26, 2025

Last Updated

January 16, 2026

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will share

The investigators will share anonymized responses from participants containing all their responses to our survey.

Shared Documents
STUDY PROTOCOL, SAP, ICF, CSR, ANALYTIC CODE
Time Frame
Indefinitely upon the study concluding.
Access Criteria
The investigators will post the data, code, and materials on Researchbox.org. The investigators will create a unique page for our project. Any interested reader can access this page.

Locations