NCT07161752

Brief Summary

This trial compares the applied forces exerted on the face of a modified preterm neonatal manikin with three different face masks. Additionally, percentages of ventilation time with mask leak \<25%, and participants' opinion about perceived applied forces, difficulty in achieving an effective ventilation, and difficulty in obtaining a good mask seal are investigated.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 2, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

September 9, 2025

Completed
6 days until next milestone

Study Start

First participant enrolled

September 15, 2025

Completed
15 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2025

Completed
Last Updated

November 20, 2025

Status Verified

November 1, 2025

Enrollment Period

15 days

First QC Date

September 2, 2025

Last Update Submit

November 17, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Applied forces

    The force applied on the manikin head by the operator during the procedure

    1 minute

Secondary Outcomes (2)

  • Mask leak

    1 minute

  • Participant opinion

    2 minutes

Study Arms (3)

Anatomical face mask 1

EXPERIMENTAL
Device: Anatomical face mask 1

Anatomical face mask 2

ACTIVE COMPARATOR
Device: Anatomical face mask 2

Round face mask

ACTIVE COMPARATOR
Device: Round face mask

Interventions

Providing face mask ventilation in a neonatal manikin using a model of anatomical face mask

Anatomical face mask 1

Providing face mask ventilation in a neonatal manikin using another model of anatomical face mask

Anatomical face mask 2

Providing face mask ventilation in a neonatal manikin using a model of round face mask

Round face mask

Eligibility Criteria

AgeUp to 65 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Level III neonatal intensive care unit (NICU) consultants, pediatric residents and anesthesiology residents

You may not qualify if:

  • Refusal to participate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Azienda Ospedaliera Università di Padova

Padua, 35128, Italy

Location

Related Publications (3)

  • Cavallin F, Zamunaro A, Maglio S, Villani PE, Bua B, Gallo D, Menciassi A, Tognarelli S, Trevisanuto D. Applied forces with partially vs. fully inflated face masks during neonatal ventilation: a randomized crossover manikin trial. Pediatr Res. 2025 Aug 27. doi: 10.1038/s41390-025-04308-2. Online ahead of print.

    PMID: 40866603BACKGROUND
  • Cavallin F, Sala C, Maglio S, Bua B, Villani PE, Menciassi A, Tognarelli S, Trevisanuto D. Applied forces with direct versus indirect laryngoscopy in neonatal intubation: a randomized crossover mannequin study. Can J Anaesth. 2023 May;70(5):861-868. doi: 10.1007/s12630-023-02402-9. Epub 2023 Feb 14.

    PMID: 36788198BACKGROUND
  • Gordon JK, Bertram VE, Cavallin F, Parotto M, Cooper RM. Direct versus indirect laryngoscopy using a Macintosh video laryngoscope: a mannequin study comparing applied forces. Can J Anaesth. 2020 May;67(5):515-520. doi: 10.1007/s12630-020-01583-x. Epub 2020 Mar 9.

    PMID: 32152886BACKGROUND

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Model Details: Manikin study
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

September 2, 2025

First Posted

September 9, 2025

Study Start

September 15, 2025

Primary Completion

September 30, 2025

Study Completion

September 30, 2025

Last Updated

November 20, 2025

Record last verified: 2025-11

Locations