NCT07157293

Brief Summary

Participants will complete one online intervention lasting 12 weeks. Each week, they will be asked to complete a 20-30 minute session online. The intervention is targeting improved mood and positive affect in order to support increases in motivation and goal-directed behavior. Before and after the intervention, participants will be asked to complete measures to assess symptoms, mood, and behavior.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
26mo left

Started Jun 2026

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress2%
Jun 2026Aug 2028

First Submitted

Initial submission to the registry

August 25, 2025

Completed
11 days until next milestone

First Posted

Study publicly available on registry

September 5, 2025

Completed
9 months until next milestone

Study Start

First participant enrolled

June 1, 2026

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2028

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2028

Last Updated

March 31, 2026

Status Verified

December 1, 2025

Enrollment Period

1.9 years

First QC Date

August 25, 2025

Last Update Submit

March 28, 2026

Conditions

Schizophrenia ProdromalSCHIZOPHRENIA 1 (Disorder)Psychosis

Keywords

negative symptomsschizophreniapsychosisdigital health

Outcome Measures

Primary Outcomes (1)

  • Brief Negative Symptom Scale

    Interview measure of motivation and pleasure

    immediately before and after the intervention

Study Arms (1)

Online Motivation Focused Intervention

EXPERIMENTAL
Behavioral: Online Motivation Enhancing Intervention

Interventions

Online Motivation Enhancing InterventionBEHAVIORAL

This is a online intervention that will ask participants to review and complete 30 minutes of material each week.

Online Motivation Focused Intervention

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosis of schizophrenia or a related psychotic disorder
  • Meeting criteria for being at clinical high risk for psychosis

You may not qualify if:

  • Does not have access to a computer each week

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Alabama at Birmingham

Birmingham, Alabama, 35223-1517, United States

Location

MeSH Terms

Conditions

Schizotypal Personality DisorderPsychotic DisordersSchizophrenia

Condition Hierarchy (Ancestors)

Personality DisordersMental DisordersSchizophrenia Spectrum and Other Psychotic Disorders

Central Study Contacts

Lauren Luther

CONTACT

205-530-1117cas-treatlab@uab.edu

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

August 25, 2025

First Posted

September 5, 2025

Study Start

June 1, 2026

Primary Completion (Estimated)

May 1, 2028

Study Completion (Estimated)

August 1, 2028

Last Updated

March 31, 2026

Record last verified: 2025-12

Data Sharing

IPD Sharing
Will not share

Locations

US(1)