Outcome of Bronchoscopy in FB Aspiration

NCT07150689 | Not Yet Recruiting

• 1 other identifier: FB bronchoscopy
• Study Type: interventional
• Target: 75
• Locations: 0 countries
• Sites: N/A

Brief Summary

Outcome of Bronchoscopy in Pediatric patient with foreign body aspiration

Conditions

Foreign Body Aspiration

Outcome Measures

Primary Outcomes (1)

• Rate of Successful Foreign Body Removal

  The proportion of patients in whom the foreign body is completely removed during the initial bronchoscopy procedure, as confirmed by direct visualization and/or post-procedure imaging.

  During bronchoscopy procedure (intra-operative, within 24 hours of intervention).

Secondary Outcomes (1)

• Incidence of procedure-related complications (within 24 hours).

  Intra-procedure and up to 24 hours post-procedure.

Study Arms (4)

Rigid Bronchoscopy

ACTIVE COMPARATOR

Standard of care in most pediatric centers; performed under general anesthesia to visualize and remove FB. Gold standard for both diagnosis and treatment

Procedure: Rigid bronchoscopy

Flexible Bronchoscop

EXPERIMENTAL

Flexible scope used for diagnosis and sometimes removal (especially in distal airways or when FB is small). Evaluate if less invasive flexible bronchoscopy can be effective.

Procedure: Flexible scope

Combined Approach

EXPERIMENTAL

Initial flexible bronchoscopy for diagnosis and airway inspection, followed by rigid bronchoscopy for removal if needed. Compare efficiency and safety of combined method.

Procedure: Combined Flexible-Rigid Bronchoscopy

Imaging-Guided Approach

EXPERIMENTAL

High-resolution CT or virtual bronchoscopy first; bronchoscopy only if imaging suggests FB. Assess if imaging can reduce unnecessary bronchoscopies.

Procedure: Imaging-Guided Bronchoscopy

Interventions

Rigid bronchoscopy PROCEDURE

Participants will undergo rigid bronchoscopy under general anesthesia using an age-appropriate rigid bronchoscope. The airway will be systematically inspected. Any identified foreign body will be removed using appropriate retrieval devices (optical forceps, retrieval basket, suction). Post-removal, the airway will be re-examined to confirm clearance and detect trauma.

Rigid Bronchoscopy

Flexible scope PROCEDURE

Participants will undergo flexible fiberoptic bronchoscopy under sedation or general anesthesia. The bronchoscope will be inserted transorally or transnasally. The airway will be inspected, and foreign body retrieval attempted using retrieval baskets, forceps, or cryoprobe

Flexible Bronchoscop

Combined Flexible-Rigid Bronchoscopy PROCEDURE

Initial flexible bronchoscopy will be performed to locate the foreign body and inspect distal airways, followed by rigid bronchoscopy for definitive removal.

Combined Approach

Imaging-Guided Bronchoscopy PROCEDURE

Participants will undergo pre-procedure high-resolution CT or virtual bronchoscopy. Based on imaging, either rigid or flexible bronchoscopy will be performed, targeting the suspected location to reduce procedure time.

Imaging-Guided Approach

Eligibility Criteria

• Age: 1 Day - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• children less than 18 years with suspected foreign body aspiration

You may not qualify if:

• children with congenital airway anomalies other than foreign body aspiration

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Respiratory Aspiration

Condition Hierarchy (Ancestors)

Respiration Disorders; Respiratory Tract Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: Masking Description
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident

Study Record Dates

• First Submitted: August 8, 2025
• First Posted: September 2, 2025
• Study Start: October 1, 2025
• Primary Completion (Estimated): October 1, 2026
• Study Completion (Estimated): October 1, 2026
• Last Updated: September 2, 2025

Record last verified: 2025-07