Institutional Experience With Chest Wall Reconstruction Using Sternal Steel Wires: A Case Series Study

NCT07148648 | Completed DMC

• 1 other identifier: IRB/2025/1653/SIMS
• Study Type: observational
• Target: 38
• Locations: 1 country
• Sites: 1

Brief Summary

Chest wall resections, often performed for tumors, infections, or trauma, result in significant defects that require reconstruction to restore structural integrity and functionality. The use of twisted stainless steel wires (No. 05) for chest wall reconstruction offers a cost-effective and practical alternative. Steel wires provide robust structural support, allow dynamic movement of the chest wall during respiration, and are associated with improved postoperative pain control.

Conditions

Chest Wall Mechanics; Chest Wall Deformity; Chest Wall Tumor; Chest Wall Disease

Keywords

sternal steel wires; chest wall reconstruction; respiratory mechanics; flail segment; chest wall tumors; chest wall resection

Outcome Measures

Primary Outcomes (1)

• Chest Wall Recoil

  Chest wall recoil after reconstruction is defined as maintenance of normal chest wall movement during respiration without paradoxical motion. It is assessed using spirometry (Forced Vital Capacity \[FVC\] and Forced Expiratory Volume in 1 second \[FEV1\]) compared with baseline/preoperative predicted values, radiological evaluation (postoperative chest X-rays for symmetrical expansion) and clinical observation (absence of paradoxical chest wall movement on examination). Preserving chest wall recoil is essential for normal breathing mechanics. Reconstruction with sternal steel wires aims to restore physiological elasticity, maintain ventilatory efficiency, and reduce respiratory complications.

  30 days post-operatively

Secondary Outcomes (1)

• Post-Operative Pain Control

  24 hours, 72 hours and 07 days

Study Arms (1)

Wires Group

all the participants who undergo chest wall reconstruction using sternal steel wires, number 05 are included in this group.

Procedure: Chest Wall Reconstruction

Interventions

Chest Wall Reconstruction PROCEDURE

there are many methods described in literature for reconstruction of chest wall after chest wall resection. The investigators are focusing on chest wall reconstruction using steel wires in this study.

Wires Group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All participants diagnosed with conditions requiring chest wall reconstruction and admitted to the thoracic surgery ward, emergency department, or outpatient department during the study period will be included in this study.

You may qualify if:

• Patients undergoing chest wall resection due to tumors or trauma.

You may not qualify if:

• Patients with contraindications to General Anesthesia.
• Patients having chest wall infection.
• Patients with pre-existing chest wall deformities or severe chronic respiratory diseases.
• Patients who undergo reoperation or develop intraoperative complications affecting the chest wall reconstruction.

Sponsors & Collaborators

• University of Health Sciences Lahore: lead

Study Sites (1)

Services Institute Of Medical Sciences (SIMS), Services Hospital, Lahore

Lahore, Punjab Province, Pakistan

Location

Study Officials

• Muhammad Shoaib Nabi, Professor Of Thoracic Surgery

  Services Institute Of Medical Sciences (SIMS), Services Hospital, Lahore

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: August 23, 2025
• First Posted: August 29, 2025
• Study Start: May 1, 2023
• Primary Completion: April 30, 2025
• Study Completion: July 31, 2025
• Last Updated: August 29, 2025

Record last verified: 2025-08

Locations

PA (1)