Video Game-facilitated Group Activity for Quality of Life and Social Function in Chronic Schizophrenia Inpatients.

NCT07148609 | Active Not Recruiting

• 1 other identifier: TTPC-114015
• Study Type: interventional
• Target: 64
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to learn if video game-facilitated group activity helps to improve the quality of life and social function in inpatients with chronic schizophrenia. The main questions it aims to answer are:

• Does video game-facilitated group activity enhance the quality of life as measured by a standardized scale (WHOQOL) in patients with schizophrenia hospitalized in a psychiatric hospital?
• Can video game-facilitated group activity promote social function as measured by a specific scale (PSP) in patients with schizophrenia hospitalized in a psychiatric hospital? Researchers will compare video game-facilitated group activity to regular occupational therapy to see if the intervention is beneficial to patients with chronic schizophrenia. Participants will:
• Attend to video game-facilitated group activity or regular occupational therapy three times a week for 12 weeks.
• Receive assessments upon and after the 12-week intervention, and another 12 weeks after the intervention ends.

Conditions

Schizophrenia Patients

Keywords

Video game; Schizophrenia; Social function; Quality of life

Outcome Measures

Primary Outcomes (2)

• The changes of quality of life

  The changes of quality of life will be assessed by the World Health Organization Quality of Life-BREF (WHOQOL-BREF).

  The outcome will be assessed at baseline, week 12, and week 24.

• The changes of social function.

  The changes of social function will be evaluated by the Personal and Social Performance Scale (PSP).

  The outcome will be assessed at baseline, week 12, and week 24

Secondary Outcomes (4)

• The changes of cerebral blood flow.

  The outcome will be assessed at baseline and week 12.

• The change of cognitive function.

  The outcome will be assessed at baseline and week 12.

• The change of psychiatric symptoms.

  The outcome will be assessed at baseline and week 12.

• The change of physical fitness

  The outcome will be assessed at baseline and week 12.

Other Outcomes (2)

• Demographic data

  Demographic data will be assessed at baseline.

• The change of daily antipsychotic dose equivalences.

  This outcome will be assessed at the baseline, Week 12, and Week 24.

Study Arms (2)

Interventional arm

ACTIVE COMPARATOR

Behavioral: Video game-facilitated group activity

Controlled arm

NO INTERVENTION

Interventions

Video game-facilitated group activity BEHAVIORAL

The intervention is a 12-week group activity program for each participant in the intervention group, and the program consists of three 50-minute video game facilitated group activity sessions per week. Participants in the intervention group will engage in those group activity session which will be mediated by the game of Super Mario Party on Nintendo Switch.

Interventional arm

Eligibility Criteria

• Age: 20 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Individuals aged between \>18 and \<65 years with a principal diagnosis of schizophrenia, as defined by the International Classification of Diseases (ICD-10) codes F20.0-F20.9 which was diagnosed according to DSM-5-TR criteria.
• Possessing a valid Catastrophic Illness Certificate for schizophrenia and being continuously hospitalized for more than six months.
• Being able to read Chinese and communicate effectively in either Mandarin or Taiwanese.
• Being able to comprehend the purpose of the study and to provide written informed consent after the study has been explained by the researchers.

You may not qualify if:

• Individuals exhibiting unstable psychiatric or consciousness conditions, or those unable to comply with video game-based instruction and operation.
• Individuals with a history of ocular diseases, severe cardiovascular disorders, epilepsy, or brain injuries; or those who have experienced acute cardiovascular or cerebrovascular events, bone fractures, undergone hip or knee joint replacement, or present with lower limb balance impairments or structural injuries-such as amputations, post-lumbar surgery status, or acute ankle sprains-rendering participation unsuitable within the past six months.
• Concurrent participation in other research studies during the study period, where the intervention may potentially influence the primary or secondary outcomes of this study.
• Individuals who are legally declared under guardianship.

Sponsors & Collaborators

• TsaoTun Psychiatric Center, Department of Health, Taiwan: lead

Study Sites (1)

Tsao-Tun Psychiatric Center, Ministry of Health and Welfare

Nantou City, Taiwan, 54249, Taiwan

Location

MeSH Terms

Conditions

Schizophrenia; Social Adjustment

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders; Social Behavior; Behavior

Study Officials

• Yung-Jen Yang

  Tsao-Tun Psychiatric Center

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident psychiatrist

Study Record Dates

• First Submitted: August 23, 2025
• First Posted: August 29, 2025
• Study Start: May 3, 2025
• Primary Completion: March 31, 2026
• Study Completion: March 31, 2026
• Last Updated: August 29, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)