Surgical Treatment of Functional Popliteal Artery Entrapment Syndrome: Results of a Systematic Approach Based on the Section of the Medial Gastrocnemius Attachment

NCT07147556 | Not Yet Recruiting

• 2 other identifiers: APHP2510982025-A01670-49
• Study Type: observational
• Target: 70
• Locations: 0 countries
• Sites: N/A

Brief Summary

Functional popliteal artery entrapment syndrome (FPAES) is a rare unique clinical entity that does not have associated with anatomic abnormalities and, therefore, is thought to be functional in nature (1,2). It has been first described by Rignault et al. in 1985, and its true mechanism is not well understood (3,4). Given the relative lack of knowledge of FPAES in the literature and the reported outcomes after decompressive surgery are limited and not standardized. The objective of this study was to describe our diagnostic and peri-operative protocol, clinical outcomes of a unique surgical management technique based on the systemic section of the attachment of the medial head of the gastrocnemius.

Conditions

Popliteal Artery Entrapment Syndrome

Keywords

Functional popliteal artery entrapment syndrome; Surgical treatment; Systematic approach; Athlete; Decompression

Outcome Measures

Primary Outcomes (1)

• To evaluate the clinical and functional improvement, and the return to the sportive level

  Clinical improvement was defined as the ability to increase activity or decreased discomfort of the initial presenting symptoms. To evaluate objectively the functional improvement as well as to assess the effectiveness of the surgical intervention, the Lower Extremity Functional Scale (LEFS) will be used post operatively at 1 year post operativeley

  at 1 year

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients who underwent surgical treatment of FPAES between 2015 and 2025

You may qualify if:

• All patients who underwent surgical treatment of functional popliteal artery entrapment syndrome between 2015 and 2025 and agree to participate in the study

Sponsors & Collaborators

• Assistance Publique - Hôpitaux de Paris: lead

Related Publications (5)

• Singh N. Functional popliteal entrapment: A diagnostic and treatment conundrum. J Vasc Surg. 2019 Nov;70(5):1563. doi: 10.1016/j.jvs.2019.02.019. No abstract available.

  PMID: 31653376 BACKGROUND

• Hislop M, Kennedy D, Cramp B, Dhupelia S. Functional Popliteal Artery Entrapment Syndrome: Poorly Understood and Frequently Missed? A Review of Clinical Features, Appropriate Investigations, and Treatment Options. J Sports Med (Hindawi Publ Corp). 2014;2014:105953. doi: 10.1155/2014/105953. Epub 2014 Sep 7.

  PMID: 26464888 BACKGROUND

• Rignault DP, Pailler JL, Lunel F. The "functional" popliteal entrapment syndrome. Int Angiol. 1985 Jul-Sep;4(3):341-3.

  PMID: 3831156 BACKGROUND

• Turnipseed WD. Functional popliteal artery entrapment syndrome: A poorly understood and often missed diagnosis that is frequently mistreated. J Vasc Surg. 2009 May;49(5):1189-95. doi: 10.1016/j.jvs.2008.12.005.

  PMID: 19394547 BACKGROUND

• Binkley JM, Stratford PW, Lott SA, Riddle DL. The Lower Extremity Functional Scale (LEFS): scale development, measurement properties, and clinical application. North American Orthopaedic Rehabilitation Research Network. Phys Ther. 1999 Apr;79(4):371-83.

  PMID: 10201543 BACKGROUND

MeSH Terms

Conditions

Popliteal Artery Entrapment Syndrome

Condition Hierarchy (Ancestors)

Arterial Occlusive Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Raphaël COSCAS, MD, PhD

  CHU Ambroise Paré - APHP

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Raphaël COSCAS, MD, PhD

CONTACT

01 49 09 55 85; raphael.coscas@aphp.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 22, 2025
• First Posted: August 29, 2025
• Study Start: October 1, 2025
• Primary Completion (Estimated): November 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: September 8, 2025

Record last verified: 2025-09