Scalp Block Versus General Anesthesia in Patients Undergoing Evacuation of Subdural Hematoma Via Burr Hole

NCT07143799 | Recruiting

• 1 other identifier: Soh-Med--25-8-8MS
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

this study amis to compare between Scalp block versus general anesthesia in patients undergoing evacuation of subdural hematoma via burr hole.

Conditions

Subdural Hematoma

Outcome Measures

Primary Outcomes (1)

• The aim of this prospective randomized study is to compare Scalp block versus general anesthesia in patients undergoing evacuation of subdural hematoma via burr hole.

  Post operative scale by The Glasgow Coma Scale (GCS) and post operative hemodynamics.

  24 hours after operation

Study Arms (2)

'Group A will receive general anesthesia

ACTIVE COMPARATOR

Induction of general anesthesia will be done by IV propofol 2-2.5 mg / kg and IV fentanyl lug/kg. After IV Cis-atracurium 0.15mg/kg, endotracheal intubation will be done.

Drug: Cisatracurium

Group B patients will receive scalp block

ACTIVE COMPARATOR

The scalp block will target six pairs of sensory nerves that innervate the scalp: the supraorbital nerve, supratrochlear nerve, auriculotemporal nerve, zygomaticotemporal nerve, greater occipital nerve, and lesser occipital nerve.Local anesthetic (2% lidocaine and bupivacaine) will be infiltrated at specific anatomical landmarks corresponding to the course of each nerve

Other: scalp block

Interventions

Cisatracurium DRUG

Induction of general anesthesia will be done by IV propofol 2-2.5 mg / kg and IV fentanyl lug/kg. After IV Cis-atracurium 0.15mg/kg, endotracheal intubation will be done.

'Group A will receive general anesthesia

scalp block OTHER

The scalp block will target six pairs of sensory nerves that innervate the scalp: the supraorbital nerve, supratrochlear nerve, auriculotemporal nerve, zygomaticotemporal nerve, greater occipital nerve, and lesser occipital nerve. Local anesthetic (2% lidocaine and bupivacaine) will be infiltrated at specific anatomical landmarks corresponding to the course of each nerve.

Group B patients will receive scalp block

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age from 18 to 75 years old.
• Both sexes.
• American Society of Anesthesiologists (ASA) physical status II-III.
• Patients with subdural hematoma undergoing burr-hole evacuation

You may not qualify if:

• Patients with a history of known sensitivity to study drugs.
• Glasgow Coma Scale (GCS) \<8
• Impaired coagulation profile.
• Any degree of heart block.
• Infection at site of injection

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag university hospital

Sohag, Egypt

RECRUITING

Related Publications (3)

• Scruton TJ. Updates on the diagnosis and management of subdural hematoma. JAAPA. 2024 Aug 1;37(8):9-15. doi: 10.1097/01.JAA.0000000000000055. Epub 2024 Jul 25.

  PMID: 38980290 BACKGROUND

• Knopman J, Link TW, Navi BB, Murthy SB, Merkler AE, Kamel H. Rates of Repeated Operation for Isolated Subdural Hematoma Among Older Adults. JAMA Netw Open. 2018 Oct 5;1(6):e183737. doi: 10.1001/jamanetworkopen.2018.3737.

  PMID: 30646255 BACKGROUND

• Sharma R, Rocha E, Pasi M, Lee H, Patel A, Singhal AB. Subdural Hematoma: Predictors of Outcome and a Score to Guide Surgical Decision-Making. J Stroke Cerebrovasc Dis. 2020 Nov;29(11):105180. doi: 10.1016/j.jstrokecerebrovasdis.2020.105180. Epub 2020 Aug 7.

  PMID: 33066943 BACKGROUND

MeSH Terms

Conditions

Hematoma, Subdural

Interventions

cisatracurium

Condition Hierarchy (Ancestors)

Intracranial Hemorrhage, Traumatic; Intracranial Hemorrhages; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Craniocerebral Trauma; Trauma, Nervous System; Vascular Diseases; Cardiovascular Diseases; Hematoma; Hemorrhage; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Wounds and Injuries

Central Study Contacts

Mohamed H elsayed, Resident

CONTACT

01050053614; sakr422022@gmail.com

Abdel Rahman H Abdel Rahman, Professor

CONTACT

01120320258

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident , Anesthesia , Surgical Icu , Pain management Faculty of Medicine Sohag university

Study Record Dates

• First Submitted: August 13, 2025
• First Posted: August 27, 2025
• Study Start: August 11, 2025
• Primary Completion: March 20, 2026
• Study Completion: March 20, 2026
• Last Updated: August 27, 2025

Record last verified: 2025-08

Locations

EG (1)