Endoscopic Findings in Iron Deficiency Anemia: A Cross-Sectional Study From Port Sudan

NCT07143435 | Completed DMC

• 1 other identifier: EndoscopicFindingsIronDef
• Study Type: observational
• Target: 117
• Locations: 1 country
• Sites: 1

Brief Summary

Background: Iron deficiency anemia (IDA) is a common condition often linked to gastrointestinal blood loss, making endoscopic evaluation essential for identifying underlying causes. This study aimed to assess the endoscopic findings in patients presenting with IDA in Red Sea State, Sudan. Understanding the prevalence and types of gastrointestinal lesions among these patients can aid in early diagnosis and management, reducing associated morbidity and mortality. By focusing on patients undergoing endoscopic evaluation, this study provides valuable insights into the burden of gastrointestinal pathologies contributing to IDA in the region. Materials and Methods: This cross-sectional, descriptive study was conducted in the Endoscopy Unit at Alkaleej Medical Complex - Portsudan. Adults aged ≥18 years with IDA undergoing endoscopic evaluation were included, excluding those unwilling participation or with incomplete data. Data were collected via structured questionnaires and medical records, covering demographics, medical history, clinical presentation, and endoscopic findings. SPSS version 26 - 2018, was used for analysis, applying descriptive statistics and chi-square tests to assess associations. Ethical approval was obtained, and informed consent was secured from all participants.

Conditions

Iron Deficiency Anemia; Endoscopy; Anemia

Keywords

Sudan; Gastrointestinal blood loss; Endoscopic findings

Outcome Measures

Primary Outcomes (1)

• Proportion of patients with endoscopic lesions explaining iron deficiency anemia

  Percentage of participants with one or more endoscopic findings potentially accounting for IDA (e.g., gastric/duodenal ulcer, gastritis with bleeding, colonic mass/ulcer, angiodysplasia), confirmed by endoscopy ± biopsy when indicated.

  4 months

Secondary Outcomes (1)

• Proportion of biopsy-proven malignancies

  4 months

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study population consisted of all patients presenting with IDA who underwent endoscopic evaluation at the study site during the study period.

You may qualify if:

• Adults aged 18 years and above.
• Patients diagnosed with IDA who underwent endoscopic evaluation.

You may not qualify if:

• Patients who declined to participate in the study.
• Patients with incomplete medical records or missing endoscopic findings.

Sponsors & Collaborators

• National Center for Gastroentestinal and Liver Disease: lead

Study Sites (1)

Alkhaleej Medical Center

Kassala, 21111, Sudan

Location

MeSH Terms

Conditions

Anemia, Iron-Deficiency; Anemia

Condition Hierarchy (Ancestors)

Anemia, Hypochromic; Hematologic Diseases; Hemic and Lymphatic Diseases; Iron Deficiencies; Iron Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Officials

• Mohammed Ganim, Dr.

  National Center for Gastrointestinal And Liver Diseases

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 9, 2025
• First Posted: August 27, 2025
• Study Start: February 11, 2019
• Primary Completion: April 12, 2020
• Study Completion: August 17, 2021
• Last Updated: August 27, 2025

Record last verified: 2025-08

Locations

SU (1)