Investigation of the Relationship Between Nutritional Status Assessment and Frailty in Critical Care Patients

NCT07143084 | Enrolling By Invitation

• 1 other identifier: 02.05.2025_E-25-426
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to understand the effects of these two parameters on clinical outcomes by examining the relationship between NUTRIC and CONUT scores in intensive care patients. The results of the study may contribute to the development of new approaches to the treatment process of patients by better understanding the relationship between nutritional status and pre-hospital frailty in intensive care units. In addition, eliminating the deficiencies in this area will pave the way for the creation of more effective and personalized treatment plans for similar patients.

Conditions

Critical Illness; Fraility

Keywords

CONUT; Fraility; NUTRIC Score

Outcome Measures

Primary Outcomes (1)

• Correlation between CONUT scale and frailty in intensive care patients

  To evaluate the correlation between the CONUT scale and frailty, Pearson or Spearman correlation analysis will be performed depending on suitability for normal distribution. Logistic regression analysis will be performed to assess the independent association between CONUT scale and frailty. Potential confounding variables such as age, gender, APACHE II score, and activities of daily living will be included in the regression model.

  From enrollment 2 days

Secondary Outcomes (1)

• Association of NUTRIC score and CONUT scale with clinical outcomes

  From enrollment to through study completion an average of 1 year

Study Arms (1)

ICU Patients above 65 years old

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Over 65 years, critically ill patients, who are submitted to ICU.

You may qualify if:

• over 65
• hours min. ICU stay

You may not qualify if:

• Patients who are under 65 years of age
• whose intensive care stay does not exceed 48 hours
• who have missing data for serum albumin or lymphocyte count or total cholesterol,
• who have been diagnosed with hematological diseases such as leukemia or lymphoma

Sponsors & Collaborators

• Ankara Training and Research Hospital: lead

Study Sites (1)

Ankara Training And Research Hospital

Altındağ, Ankara, 06230, Turkey (Türkiye)

Location

Related Publications (3)

• Auza-Santivañez, J. C., Perez, J. S., Lara, Y. D., León, D. O., Condori-Villca, N., & Loaces, J. P. A. Predictive value of the CONUT scale in the early detection of nutritional risk and its relationship with mortality in critically ill patients.

  BACKGROUND

• Kos, M., Titiz, H., Onec, B., Soysal, T., Kutlucan, A., Emen, S. S., & Kutlucan, L. (2016). Association of "controlling nutritional status index" and "prognostic nutritional index" with intensive care unit survival in elderly patients. European Geriatric Medicine, 7(1), 13-17.

  BACKGROUND

• Lo Buglio A, Bellanti F, Capurso C, Vendemiale G. Controlling Nutritional Status (CONUT) Score as a Predictive Marker in Hospitalized Frail Elderly Patients. J Pers Med. 2023 Jul 10;13(7):1119. doi: 10.3390/jpm13071119.

  PMID: 37511732 BACKGROUND

MeSH Terms

Conditions

Critical Illness

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 2 Days
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: June 25, 2025
• First Posted: August 27, 2025
• Study Start: May 15, 2025
• Primary Completion (Estimated): December 15, 2026
• Study Completion (Estimated): May 1, 2027
• Last Updated: March 19, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF, CSR

Locations

TU (1)