The Effects of Kinesiophobia and Proprioception on Disability and Function in Rheumatoid Hand

NCT07141927 | Completed

• 1 other identifier: SCU-FTR-SB-03
• Study Type: observational
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

This is a cross-sectional study aimed at examining the effects of kinesiophobia and proprioception on disability and function in the rheumatoid hand, compared to healthy controls.

Conditions

Rheumatoid Arthritis (RA)

Keywords

Disability; Function; Joint reposition sense; Kinesiophobia; Rheumatoid hand; Muscle strength

Outcome Measures

Primary Outcomes (4)

• Kinesiophobia

  The participant's fear-avoidance behavior toward physical activity was assessed using the Tampa Kinesiophobia Scale.

  First day

• Wrist-thumb proprioception

  Joint position sense for wrist extension and thumb carpometacarpal flexion was assessed with goniometry. Joint position sense was measured by the ability to actively replicate a pre-determined target angle (30 degrees). During the measurement, the participant's evaluated joints was brought to the target angle and held in this position for three seconds. The participant was asked to hold this position in their memory, after which the joints will be passively returned to the starting position. Then, the participant was asked to actively move their hand to these pre-determined positions. The result was determined by the average deviation angle obtained from the measurements repeated at thirty-second intervals. These measurement were only taken with the dominant hand.

  First day

• Hand function

  Hand function was evaluated with the Dellon Modifiye Moberg pickup test.

  First day

• Hand disability

  Hand disability was evaluated with the Disabilities of the Arm, Shoulder, and Hand

  First day

Secondary Outcomes (4)

• Demographic characteristics

  First day

• Disease activity

  First day

• Physical activity level

  First day

• Isometric wrist extensor muscle strength measurement

  First day

Study Arms (2)

RA group

RA volunteers followed in the rheumatology outpatient clinic of a university hospital

Other: Measurements

Healthy controls

Hospital staff and volunteer companions of these RA patients

Other: Measurements

Interventions

Measurements OTHER

First, the demographic characteristics of all participants were recorded. For those who met the inclusion criteria, primary and secondary outcome measurements were performed by the same physical therapist in a single session

Healthy controls; RA group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Volunteer patients receiving treatment and follow-up at the rheumatology outpatient clinic of a university hospital formed the study sample. The healthy control group included hospital staff and volunteer companions of these patients.

You may qualify if:

• Diagnosis of RA
• Volunteering
• Being between the ages of 18 and 65
• Being healthy.
• Being between 18-65 years old.
• Being a volunteer

You may not qualify if:

• The presence of another rheumatic disease or chronic illness that could affect function and cause disability.
• Pain, deformity, or other cooperation issues (such as severe mental, visual, or hearing impairments) that prevent participation in measurements.
• Sensory loss in the upper extremity, history of surgery, and injury in the last six months.
• Any diagnosis of chronic or acute illness.
• In the upper extremity, history of surgery injury in the last six months.

Sponsors & Collaborators

• Cumhuriyet University: lead

Study Sites (1)

Sivas Cumhuriyet University

Sivas, 58140, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Arthritis, Rheumatoid; Kinesiophobia

Interventions

Weights and Measures

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Connective Tissue Diseases; Skin and Connective Tissue Diseases; Autoimmune Diseases; Immune System Diseases; Phobic Disorders; Anxiety Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Investigative Techniques

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: associate professor, Ph.D.

Study Record Dates

• First Submitted: August 19, 2025
• First Posted: August 26, 2025
• Study Start: April 18, 2023
• Primary Completion: November 28, 2023
• Study Completion: July 28, 2024
• Last Updated: August 26, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)