Effect of Nebulized Lignocaine on the Stress Response of Endotracheal Intubation in Pediatrics Undergoing Tonsillectomy Operation Monitored by Rise in Serum Cortisol Level Post Intubation
1 other identifier
interventional
70
0 countries
N/A
Brief Summary
This randomized clinical trial aims to is examining the effect of preoperative nebulized lidocaine on the stress response to intubation, monitored by rise in serum cortisol level post intubation
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Sep 2025
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
August 18, 2025
CompletedFirst Posted
Study publicly available on registry
August 24, 2025
CompletedStudy Start
First participant enrolled
September 1, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
October 1, 2026
August 24, 2025
August 1, 2025
1 year
August 18, 2025
August 22, 2025
Conditions
Outcome Measures
Primary Outcomes (2)
effect on serum cortisol level 2 minutes after intubation
baseline
effect on serum cortisol level 2 minutes after intubation
effect on serum cortisol level 2 minutes after intubation to asses decrease in stress response
baseline
Study Arms (1)
Effect of Nebulized Lignocaine on the stress Response of Endotracheal Intubation in pediatrics unde
EXPERIMENTALInterventions
the effect of preoperative nebulized lidocaine on the stress response to intubation, monitored by rise in serum cortisol level post intubation
Eligibility Criteria
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Sponsors & Collaborators
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- doctor
Study Record Dates
First Submitted
August 18, 2025
First Posted
August 24, 2025
Study Start
September 1, 2025
Primary Completion (Estimated)
September 1, 2026
Study Completion (Estimated)
October 1, 2026
Last Updated
August 24, 2025
Record last verified: 2025-08