FRench Elective Oocyte prEservation: a Multicenter Study thrEe Years Later

NCT07138469 | Completed

• 1 other identifier: BRUGNON_2023_CF094
• Study Type: observational
• Target: 351
• Locations: 1 country
• Sites: 1

Brief Summary

Previously reserved for pathological cases, oocyte cryopreservation for non-medical reason also named elective fertility preservation (EFP) is now authorized in France for women aged 29 to 37 following the revision of the bioethics law on August 2nd 2021. Currently, French data related to this new practice are lacking. The aim of this study is to conduct a preliminary assessment 3 years after approval of elective oocyte cryopreservation in France, evaluating the knowledge and perspectives of women undergoing elective fertility preservation in order to gain a better understanding of this new population and define the socio-economic and demographic profiles to improve care quality.

Conditions

Elective Fertility Preservation

Outcome Measures

Primary Outcomes (1)

• Questionnaire to better define the demographic characteristics, knowledge, and perspectives of women who have undergone or wish to undergo oocyte cryopreservation for non-medical reasons.

  Department of residence, age group, stage of process, family status, marital status, education level, motivation, sources of information, knowledge of limit age for oocyte use, probability of use, perspectives of using cryopreserved oocytes: intended family model, perspectives in case of non-use of cryopreserved oocytes, knowledge of the bioethics law on the right of access to origins governing gamete donation

  7 months (01/11/2023 to 30/06/2024)

Secondary Outcomes (1)

• Analysis of questionnaire responses based on whether or not fertility preservation has been performed, to assess the impact of the care stage on knowledge of the bioethics law.

  7 months (01/11/2023 to 30/06/2024)

Study Arms (1)

women engaged in an elective fertility preservation process

women engaged in an elective fertility preservation process and who agree to participate in the study by completing the questionnaire

Other: Questionnaire

Interventions

Questionnaire OTHER

The questionnaire was offered on a voluntary basis and completed online by the participants. At the end of the inclusion period, the responses were analyzed. Participant indicated in the questionnaire whether or not they had already undergone oocyte cryopreservation. The responses were analyzed to assess demographic characteristics, the level of knowledge regarding the bioethics law on non-medical fertility preservation, and future perspectives in the event of use (desired parental model, likelihood of use) or non-use.

Also known as: Questionnaire developed by the AMP-CECOS unit of the Clermont-Ferrand University Hospital and approved by the ART unit team.

women engaged in an elective fertility preservation process

Eligibility Criteria

• Age: 29 Years - 37 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

women engaged in an elective fertility preservation process and who agree to participate in the study by completing the questionnaire

You may qualify if:

• Being in SFP process
• Undergone SFP
• to 37 years of age at the time of SFP or process

You may not qualify if:

• Women who had criteria for medical fertility preservation

Sponsors & Collaborators

• University Hospital, Clermont-Ferrand: lead

Study Sites (1)

CHU de Clermont-Ferrand

Clermont-Ferrand, Auvergne, 63000, France

Location

MeSH Terms

Interventions

Surveys and Questionnaires

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Jeanne Dufaure, MD

  University Hospital, Clermont-Ferrand

  PRINCIPAL INVESTIGATOR

• Florence Brugnon, MD,PhD,HDR

  University Hospital, Clermont-Ferrand

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 25, 2025
• First Posted: August 22, 2025
• Study Start: November 1, 2023
• Primary Completion: June 30, 2024
• Study Completion: June 30, 2024
• Last Updated: August 22, 2025

Record last verified: 2025-06

Locations

FR (1)