Impact of Erector Spinae Plane Block on Systemic Immune-inflammation Index

NCT07137702 | Completed

• 1 other identifier: 2025-225
• Study Type: observational
• Target: 127
• Locations: 1 country
• Sites: 1

Brief Summary

The primary objective of the study is to determine whether there is a relationship between postoperative SII and erector spinae plane block application. If data emerges indicating a more suppressed inflammatory response in patients undergoing block, widespread use of this block in the specified patient group would reflect the clinical significance of the study. The searches did not uncover any studies investigating the effects of trunk blocks, such as erector spinae plane block, on postoperative systemic inflammatory response, indicating that this study could make a significant contribution to the literature.

Conditions

Systemic Immune-inflammatory Index; Erector Spinae Plane Block; Breast Conserving Surgery

Keywords

systemic immune-inflammatory index; erector spinae plane block; breast conserving surgery

Outcome Measures

Primary Outcomes (1)

• systemic immune-inflammation index

  Platelet count × Neutrophil count / Lymphocyte count

  7 days after surgery

Study Arms (2)

ESPB + group

the patients who received erector spinae plane block

Procedure: Erector Spinae Plane Block

ESPB - group

the patients who didn't receive erector spinae plane block

Interventions

Erector Spinae Plane Block PROCEDURE

A standardized perioperative care management protocol is applied for all breast-conserving surgery procedures in our department. All patients are informed about ESPB and offered its application preoperatively. Patients who accept the procedure receive ESPB (preoperatively, in the sitting position, at the level of ipsilateral T4 vertebra, USG guided, out-of-plane approach) while those who refuse are subjected to routine intravenous analgesia protocols. All blocks were performed by an anesthesiologist experienced in the application of truncal blocks and 20 cc 0.5% bupivacaine (within the safe dose range for all patients to be used according to their weight) are injected and its spread is visualized under USG.

ESPB + group

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

women who have undergone breast-conserving surgery for malignant causes

Sponsors & Collaborators

• Taner Abdullah: lead

Study Sites (1)

Basaksehir Cam ve Sakura City Hospital

Istanbul, Turkey (Türkiye)

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: MD

Study Record Dates

• First Submitted: August 16, 2025
• First Posted: August 22, 2025
• Study Start: July 15, 2025
• Primary Completion: August 15, 2025
• Study Completion: August 15, 2025
• Last Updated: August 22, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)