Effects Of Turkish Coffee Consumption On Cardiovascular Markers And Sleep In Healthy Women

NCT07133373 | Completed

• 2 other identifiers: UPetraE/H/5/10/2024
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This randomized controlled trial aims to evaluate the short-term effects of daily unfiltered Turkish coffee consumption on cardiovascular parameters, appetite-regulating hormones, glucose metabolism, inflammatory markers, and sleep quality in healthy young women. Forty participants will be randomly assigned to an intervention group, consuming standardized servings of Turkish coffee for four weeks, or to a control group abstaining from coffee during the same period. Measurements will be taken at baseline and after the intervention, including blood pressure, lipid profile, leptin, ghrelin, glucose metabolism markers, inflammatory biomarkers, body composition, and sleep quality indices.

Conditions

Effects of Turkish Coffee Consumption on Cardiovascular Markers and Sleep in Healthy Women; Cardiometabolic Health Markers, Appetite-regulating Hormones, Inflammation, and Sleep Quality in Healthy Women

Keywords

Turkish coffee; caffeine; young female; cardiovascular health; insomnia; appetite

Outcome Measures

Primary Outcomes (1)

• Change in systolic and diastolic blood pressure after 4 weeks of Turkish coffee consumption

  Systolic and diastolic blood pressure were measured at baseline and after 4 weeks using a validated electronic monitor (Omron M6). Participants were seated in a relaxed position, and the average of two readings was recorded. The change in blood pressure levels was used to assess cardiovascular effects of Turkish coffee consumption.

  Baseline and Week 4

Secondary Outcomes (1)

• Change in serum leptin and ghrelin levels after 4 week

  Baseline and Week 4

Study Arms (2)

Intervention

EXPERIMENTAL

Standardized Turkish coffee (unfiltered and boiled) was administered once daily for 4 weeks. Each serving was approximately 75 mL, prepared using a consistent protocol without added sugar or milk. The coffee was sourced from the same batch and brewed in a traditional cezve. Compliance and adverse effects were monitored throughout the intervention.

Other: Turkish Coffee (unfiltered, boiled)

control

NO INTERVENTION

Participants assigned to the control group were instructed to avoid all forms of coffee for the duration of the 4-week intervention period. They did not receive any dietary or behavioral instructions beyond abstaining from coffee consumption.

Interventions

Turkish Coffee (unfiltered, boiled) OTHER

Standardized Turkish coffee (unfiltered and boiled) was administered once daily for 4 weeks. Each serving was approximately 75 mL, prepared using a consistent protocol without added sugar or milk. The coffee was sourced from the same batch and brewed in a traditional cezve. Compliance and adverse effects were monitored throughout the intervention.

Also known as: case group

Intervention

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy female participants aged between 18 and 35 years
• Body Mass Index (BMI) between 18.5 and 29.9 kg/m²
• Habitual coffee consumers (1-2 cups/day)
• Not on a weight-loss or special medical diet
• Not taking medications or supplements that affect sleep, appetite, metabolism, or cardiovascular function
• Non-smokers and not using recreational drugs
• Willing to comply with study protocol and attend all assessments

You may not qualify if:

• Pregnancy or lactation
• Diagnosed chronic diseases (e.g., diabetes, hypertension, cardiovascular disease)
• Known sleep disorders or psychological conditions
• Allergy or sensitivity to coffee or caffeine
• Irregular menstrual cycle or hormonal disorders
• Shift workers or frequent travelers across time zones
• Participation in other clinical trials within the past 3 months

Sponsors & Collaborators

• University of Petra: lead

Study Sites (1)

UOP

Amman, 961343, Jordan

Location

MeSH Terms

Conditions

Inflammation; Sleep Initiation and Maintenance Disorders

Interventions

Diagnosis-Related Groups

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms; Sleep Disorders, Intrinsic; Dyssomnias; Sleep Wake Disorders; Nervous System Diseases; Mental Disorders

Intervention Hierarchy (Ancestors)

Prospective Payment System; Reimbursement Mechanisms; Insurance, Health, Reimbursement; Financing, Organized; Economics; Health Care Economics and Organizations

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: No blinding was implemented. Both participants and researchers were aware of group assignment due to the nature of the intervention (coffee consumption).
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Amman. Jordan

Model Details: This is a two-arm parallel randomized controlled trial. Participants were randomly assigned to either the intervention group (consuming Turkish coffee daily for 4 weeks) or the control group (no coffee consumption). Both groups were followed in parallel during the study period.

Study Record Dates

• First Submitted: August 5, 2025
• First Posted: August 21, 2025
• Study Start: August 1, 2024
• Primary Completion: October 30, 2024
• Study Completion: October 30, 2024
• Last Updated: August 21, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

JO (1)