Non-alcoholic, Fiber-enriched Beer and Its Effect on Blood Glucose Concentration

NCT07131904 | Not Yet Recruiting

• 1 other identifier: Fiberbeer trial
• Study Type: interventional
• Target: 25
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study examines how various non-alcoholic beverages affect blood sugar levels. The beverages are a non-alcoholic, fiber-enriched beer, a conventional non-alcoholic beer, and a sugar solution. Participants drink one of these beverages on different days. Afterwards, a sensor on the upper arm is used to measure the sugar content in the body fluid under the skin over a period of two hours. The aim is to find out how much blood sugar concentration rises after drinking. This will be used to check whether the non-alcoholic, fiber-enriched beer has a more favorable effect on sugar metabolism than conventional beverages. Participation is voluntary, and the data will be treated confidentially.

Conditions

Blood Glucose Concentration; Glycemic Index; Dietary Fiber; Non-alcoholic Beer

Keywords

fiber-enriched beer; functional food; continuous glucose monitoring; postprandial glucose response

Outcome Measures

Primary Outcomes (1)

• Incremental Area Under the Curve (iAUC) for Postprandial Blood Glucose

  Incremental area under the curve for interstitial glucose concentration measured over 120 minutes after beverage consumption. Measurements obtained via continuous glucose monitoring (FreeStyle Libre 3) in a randomized crossover design.

  0-120 minutes after beverage consumption on each test day

Secondary Outcomes (1)

• Glycemic Index of Fiber-Enriched Beer (FEB)

  0-120 minutes after beverage consumption on each test day

Study Arms (3)

non-alcoholic, fiber-enriched beer (FEB)

EXPERIMENTAL

Other: non-alcoholic, fiber-enriched beer (FEB)

conventional, non-alcoholic beer

ACTIVE COMPARATOR

Other: conventional, non-alcoholic beer

glucose solution

ACTIVE COMPARATOR

Other: glucose solution

Interventions

non-alcoholic, fiber-enriched beer (FEB) OTHER

500 ml FEB consumed once during a test day in a randomized crossover design. Postprandial blood glucose is monitored for 120 minutes using a continuous glucose monitor (FreeStyle Libre 3).

non-alcoholic, fiber-enriched beer (FEB)

conventional, non-alcoholic beer OTHER

500 ml conventional non-alcoholic beer consumed once during a test day in a randomized crossover design. Postprandial blood glucose is monitored for 120 minutes using a continuous glucose monitor (FreeStyle Libre 3).

conventional, non-alcoholic beer

glucose solution OTHER

Glucose solution containing 12.5 g glucose in 500 ml water, consumed once during a test day in a randomized crossover design. Postprandial blood glucose is monitored for 120 minutes using a continuous glucose monitor (FreeStyle Libre 3).

glucose solution

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy adults aged 18-60 years
• Body mass index (BMI) between 18.5 and 29.9 kg/m²
• Signed informed consent

You may not qualify if:

• Diagnosed diabetes
• Gastrointestinal diseases
• Hormonal or other metabolic diseases
• Allergies or intolerances to beer ingredients
• Professional sports (\>10 hours/week of intense exercise)
• Special diets (e.g., low-carb, intermittent fasting)
• Sleep disorders or inability to maintain regular sleep (e.g., shift work)
• Pregnancy or breastfeeding
• Smoking
• Inability to speak German or English
• Problems with alcohol, drug, or medication abuse
• Inability to sign informed consent

Sponsors & Collaborators

• David Faeh: lead

MeSH Terms

Interventions

Congresses as Topic

Intervention Hierarchy (Ancestors)

Organizations; Health Care Economics and Organizations

Central Study Contacts

David Fäh, Prof.Dr.med

CONTACT

+41 31 848 45 51; david.faeh@bfh.ch

Neeser Lorena, Bsc

CONTACT

+41 77 423 18 45; lorena.neeser@bfh.ch

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Prof. Dr. med. David Fäh

Study Record Dates

• First Submitted: August 13, 2025
• First Posted: August 20, 2025
• Study Start: August 12, 2025
• Primary Completion: September 22, 2025
• Study Completion: October 15, 2025
• Last Updated: August 20, 2025

Record last verified: 2025-08