NCT07126769

Brief Summary

This study examines how searching for health information on the internet may affect stress and emotional well-being in women undergoing infertility treatment. Infertility is a common condition that impacts about 48 million couples worldwide and can cause not only physical challenges but also significant emotional strain, including anxiety, depression, and stress. Many women turn to the internet to seek answers about their condition and treatment. While online information can be helpful, it is not always accurate or consistent, which can increase worry and confusion. This repeated and sometimes excessive searching for health information, known as "cyberchondria," has been linked in previous research to increased stress and anxiety. This study will assess women's online information-seeking patterns, infertility-related stress, and overall emotional and social well-being, aiming to better understand the role of cyberchondria in the infertility treatment process. The results may help healthcare professionals offer more targeted support and guidance to women facing these challenges.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
201

participants targeted

Target at P75+ for all trials

Timeline
1mo left

Started Sep 2025

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress92%
Sep 2025May 2026

First Submitted

Initial submission to the registry

August 11, 2025

Completed
6 days until next milestone

First Posted

Study publicly available on registry

August 17, 2025

Completed
15 days until next milestone

Study Start

First participant enrolled

September 1, 2025

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 30, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2026

Last Updated

September 30, 2025

Status Verified

September 1, 2025

Enrollment Period

9 months

First QC Date

August 11, 2025

Last Update Submit

September 25, 2025

Conditions

Outcome Measures

Primary Outcomes (4)

  • Introductory Information Form

    This form includes 24 questions divided into four sections covering women's sociodemographic details, health information, digital health search behaviors, and reproductive health.

    At baseline (one-time assessment at enrollment)

  • Screening Tool on Distress in Fertility Treatment (SCREEN-IVF)

    A 28-item scale assessing psychosocial risk factors in individuals undergoing infertility treatment. It includes subscales for anxiety, social support, helplessness, acceptance, and depression. Scores above specific cutoff points indicate elevated risk levels in these areas.

    At baseline (one-time assessment at enrollment)

  • Infertility Stress Scale

    Consists of 14 items across three subscales: Personal Stress (6 items), Marital Stress (4 items), and Social Stress (4 items). Higher scores reflect increased stress levels. Items are rated on Likert scales, with score ranges for each subscale indicating the severity of stress.

    At baseline (one-time assessment at enrollment)

  • Short Form of the Cyberchondria Severity Scale

    A 12-item scale measuring severity of excessive online health searches, covering Excessiveness, Distress, Reassurance, and Compulsion subscales. Items scored on a 5-point Likert scale. Higher total scores indicate greater cyberchondria severity

    At baseline (one-time assessment at enrollment)

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Women aged 18 to 45 undergoing infertility treatment (IUI, IVF, ICSI), who speak Turkish, consent to participate, and have no psychological disorders.

You may qualify if:

  • Women undergoing infertility treatment and those who have experienced various treatment methods (IUI, IVF, ICSI).
  • Women willing to participate in the study.
  • Women who understand and speak Turkish.

You may not qualify if:

  • Women with psychological disorders (e.g., clinical depression, anxiety disorders).
  • Women not undergoing infertility treatment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Acıbadem University

Istanbul, Ataşehir, Turkey (Türkiye)

RECRUITING

Related Publications (9)

  • Boivin J, Takefman J, Braverman A. The fertility quality of life (FertiQoL) tool: development and general psychometric properties. Hum Reprod. 2011 Aug;26(8):2084-91. doi: 10.1093/humrep/der171. Epub 2011 Jun 10.

    PMID: 21665875BACKGROUND
  • Brochu F, Robins S, Miner SA, Grunberg PH, Chan P, Lo K, Holzer HEG, Mahutte N, Ouhilal S, Tulandi T, Zelkowitz P. Searching the Internet for Infertility Information: A Survey of Patient Needs and Preferences. J Med Internet Res. 2019 Dec 12;21(12):e15132. doi: 10.2196/15132.

    PMID: 31829963BACKGROUND
  • Buran, G., Toptaş Acar, B. The effect of social and emotional capacities on coping strategies and stress in infertile individuals. Curr Psychol 43, 29984-29994 (2024). https://doi.org/10.1007/s12144-024-06504-5

    BACKGROUND
  • Çakı, B., & Sohbet, R. (2021). The examination of reproductive information and stress levels of fertilite and infertile women. Adıyaman Üniversitesi Sağlık Bilimleri Dergisi, 7(1), 103-112.

    BACKGROUND
  • European Society of Human Reproduction and Embryology (ESHRE). (2021, August). Factsheet on infertility - prevalence, treatment and fertility decline in Europe.

    BACKGROUND
  • Irmak Vural P, Korpe G, Aslan E. Validity and Reliability of the Turkish Version of Screening Tool on Distress in Fertility Treatment (SCREENIVF). Psychiatr Danub. 2021 Dec;33(Suppl 13):278-287.

    PMID: 35150496BACKGROUND
  • Mayette E, Scalise A, Li A, McGeorge N, James K, Mahalingaiah S. Assisted reproductive technology (ART) patient information-seeking behavior: a qualitative study. BMC Womens Health. 2024 Jun 15;24(1):346. doi: 10.1186/s12905-024-03183-z.

    PMID: 38877503BACKGROUND
  • Verhaak CM, Lintsen AM, Evers AW, Braat DD. Who is at risk of emotional problems and how do you know? Screening of women going for IVF treatment. Hum Reprod. 2010 May;25(5):1234-40. doi: 10.1093/humrep/deq054. Epub 2010 Mar 13.

    PMID: 20228392BACKGROUND
  • Starcevic V, Schimmenti A, Billieux J, Berle D. Cyberchondria in the time of the COVID-19 pandemic. Hum Behav Emerg Technol. 2021 Jan;3(1):53-62. doi: 10.1002/hbe2.233. Epub 2020 Nov 23.

    PMID: 33363277BACKGROUND

MeSH Terms

Conditions

Infertility

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital Diseases

Central Study Contacts

Güzin Ünlü Suvari, Ph.D. (c)

CONTACT

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Target Duration
1 Day
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer

Study Record Dates

First Submitted

August 11, 2025

First Posted

August 17, 2025

Study Start

September 1, 2025

Primary Completion (Estimated)

May 30, 2026

Study Completion (Estimated)

May 30, 2026

Last Updated

September 30, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will not share

Individual participant data (IPD) will not be publicly shared due to privacy concerns and the sensitive nature of maternal and infant health information. However, anonymized data may be made available upon reasonable request to the corresponding author after publication of the study results.

Locations