NCT07125612

Brief Summary

We aimed to explore the influence of ABT on the incidence of MINS, AKI, and overall prognosis among advanced-age HCC patients who underwent hepatectomy

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
487

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2016

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2016

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2018

Completed
6.4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2025

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

August 9, 2025

Completed
6 days until next milestone

First Posted

Study publicly available on registry

August 15, 2025

Completed
Last Updated

August 15, 2025

Status Verified

August 1, 2025

Enrollment Period

3 years

First QC Date

August 9, 2025

Last Update Submit

August 9, 2025

Conditions

Myocardial InjuryAcuter Kidney Injury

Keywords

perioperative allogeneic red blood cell transfusionelderly surgical patients

Outcome Measures

Primary Outcomes (1)

  • the incidence of MINS within postoperative 30 days

    postoperative day 1-30

Secondary Outcomes (2)

  • overall survival (OS)

    postoperative day 1-30

  • postoperative 7-day AKI

    postoperative day 1-7

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

age ≥65 years old patients

You may qualify if:

  • Patients over 65 years with HCC undergoing elective surgery between January 2016 and December 2018

You may not qualify if:

  • ASA grade V requiring repeat surgery within 1 week losing to follow-up and/or those with \>5% missing data

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

August 9, 2025

First Posted

August 15, 2025

Study Start

January 1, 2016

Primary Completion

December 31, 2018

Study Completion

June 1, 2025

Last Updated

August 15, 2025

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will not share