Preventing Hospital Associated Disability in Older Patients: Individualized Nutrition and Exercise Strategy, a Feasibility Study

NCT07124338 | Active Not Recruiting

• 2 other identifiers: p-2025-187133165-00244B
• Study Type: interventional
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

Aproximately a third of persons older than 70 years lose physical function and ability to take care of themselves during a stay at a hospital. This is associated to an increased risk of readmission and mortality. Earlier research has shown that insufficient nutrition and physical activity during hospital stay, leading to a loss in muscle mass and strength, plays an important role in this fall in functionality. This study aims to examine if a structured and supervised resistance exercise, with or without an individualized nutritional plan and intervention, can prevent this fall in functional ability during hospital stay among older patients. Furthermore, this study seeks to investigate if it is feasible to carry out such a exercise and nutritional intervention in a hospital setting, and to obtain viewpoints regarding exercise and nutrition during hospital stay from older patients. This study aims to produce experience for at bigger randomized controlled study expected later in 2025

Conditions

Malnutrition Elderly; Physical Function; Sarcopenia in Elderly; Hospital Associated Deconditioning

Keywords

Older; Hospitalized; hospital associated disability; Sarcopenia; Malnutrition; Nutritional intervention; Exercise intervention

Outcome Measures

Primary Outcomes (1)

• Eligibility to enter the study

  75 % or more of screened patients eligible to enter the study, based on exclusion and inclusion criteria.

  on inclusion day

Secondary Outcomes (18)

• Inclusion and recruitment

  on inclusion day

• Adherence to protocol: Exercise team workflow

  From inclusion to discharge from the geriatric department, varying fror each participant, but estimated 3-14 days.

• Adherence to protocol: Exercise outcome

  From inclusion to discharge from the geriatric department, varying fror each participant, but estimated 3-14 days.

• Adherence to protocol: Dietician workflow

  Inclusion day

• Adherence to protocol: Nutrition outcome

  Four days after inclusion

Study Arms (1)

Exercise and nutrition intrvention

EXPERIMENTAL

During hospitalization, 2x 30 minutes of supervised exercise. Furthermore during hospitalization, an inital nutrition plan by a trained dietician, based on Nutrional risk, identifying of nutrion impact symtomes, daily nutritional intake regristration and adjustments to the nutrion plan

Other: Exercise, supervised

Interventions

Exercise, supervised OTHER

nital nutrition plan by a trained dietician, based on Nutritional risk, identifying of nutrion impact symtomes, daily nutritional intake regristration and adjustments to the nutrion plan

Exercise and nutrition intrvention

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)

You may qualify if:

• Hospitalized at the geriatric ward
• Speak Danish or English
• Ability to give informed consent

You may not qualify if:

• Moderate to severe Dementia¨
• Manifest delirium
• Requiring specialized diet (allergies, diseases requiring special diets, aiming to lose weight)

Sponsors & Collaborators

• Bispebjerg Hospital: lead
• University of Copenhagen: collaborator

Study Sites (1)

Bispebjerg Hospital

Copenhagen, Capital Region, 2400, Denmark

Location

MeSH Terms

Conditions

Sarcopenia; Malnutrition

Interventions

Exercise

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms; Nutrition Disorders; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Charlotte Suetta, Professor

  Geriatric research unit, Bispebjerg hospital, Copenhagen

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Model Details: Feasibility Study

Study Record Dates

• First Submitted: July 3, 2025
• First Posted: August 15, 2025
• Study Start: July 1, 2025
• Primary Completion: November 30, 2025
• Study Completion (Estimated): November 30, 2026
• Last Updated: January 22, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will share
• Access Criteria: Data repository, URL link within the published feasibility study

Locations

DK (1)