NCT07122375

Brief Summary

The wrist joint performs various tasks at multiple angles during daily activities, both in flexion and extension positions. Among the parameters that facilitate these tasks, strength-particularly in relation to coordination and motor control-plays a key role. Therefore, identifying potential strength deficits is important for maintaining the continuity of daily functional tasks. In the literature, a wide range of methods exist for evaluating strength, from manual tests to advanced technological devices (references). One such method, isokinetic dynamometry, is considered among the most reliable due to its ability to provide objective and standardized measurements across different types of muscle contractions (isometric, isotonic, and isokinetic). Isokinetic dynamometers yield various data including peak torque, average torque, total work, fatigue index, and torque slope. Researchers frequently interpret findings based on peak or average torque values generated during isokinetic contractions. These torque measures provide an overall representation of strength during a given movement. In wrist movements, rather than a single muscle, muscle groups are responsible for executing motion. However, when only peak or average torque at a single joint angle is assessed, the presence or absence of weakness in the movement can be detected, but it offers limited information. If weakness exists, identifying the specific joint angle at which it occurs can provide more direct insights into which muscles may be impaired. Furthermore, angle-specific profiling allows for characterization of muscle behavior throughout the movement, offering valuable information about potential kinematic disruptions. Having normative data on these profiles enables the detection of deviations from typical patterns across the full range of motion, which can be beneficial for both diagnosis and treatment planning. However, to derive such benefits, it is critical that the data be obtained using reliable methods. Reliability refers to the degree to which an instrument or technique yields consistent results across repeated measurements, and is a prerequisite for usability. Statistical Parametric Mapping (SPM) is an increasingly popular method that enables angle-specific torque analysis, providing clinically and scientifically meaningful information on muscle strength. Angle-specific mapping is considered the "gold standard" because it presents torque values across the entire joint range, eliminating the need for interpolation between angles. For example, during daily activities, the wrist joint commonly operates within a range from 40° extension to 38° flexion. Therefore, measuring strength at only one joint angle may not be sufficient to reflect the potential limitations experienced in everyday tasks. Despite its advantages, no reliability study involving SPM analysis has been found for the wrist joint. Furthermore, there is currently no study providing normative data for SPM-based analysis in the wrist. The aim of this study is to examine the reliability of angle-specific torque profile analysis during wrist flexion and extension movements and to provide normative data for healthy young adults.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Sep 2025

Shorter than P25 for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 30, 2025

Completed
15 days until next milestone

First Posted

Study publicly available on registry

August 14, 2025

Completed
18 days until next milestone

Study Start

First participant enrolled

September 1, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2025

Completed
Last Updated

August 14, 2025

Status Verified

August 1, 2025

Enrollment Period

3 months

First QC Date

July 30, 2025

Last Update Submit

August 12, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Angle Specific Torque Profile Analysis

    Raw data from the system files of the isokinetic dynamometer of both extremities of the participants who meet the criteria will be collected. SPM analysis of these raw data will be performed using the open source spm1d package in Matlab (R2021b, The Mathworks Inc, Natick, MA) software. Thus, the torque/angle data generated by the movements of both extremities through the range of motion set in the isokinetic dynamometer will be divided into 101 slices and angle-dependent torque graphs will be generated (SPM analysis). SPM analysis will be performed for wrist flexors and extensors. As a result of this analysis, the angle-dependent torque characteristics of both wrists and unilateral angle-dependent agonist/antagonist torque characteristics will be examined.

    4 months

Interventions

All assessment data will be obtained from the archival records of young healthy adults, and no new assessments will be conducted. Raw data from wrist flexion and extension evaluations performed using an isokinetic dynamometer will be utilized.

Eligibility Criteria

Age18 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

Healthy young adult participants

You may qualify if:

  • Healthy young adult participants

You may not qualify if:

  • Participants who were unable to complete the target range of motion
  • Participants with missing data

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator, Assistant Professor

Study Record Dates

First Submitted

July 30, 2025

First Posted

August 14, 2025

Study Start

September 1, 2025

Primary Completion

December 1, 2025

Study Completion

December 1, 2025

Last Updated

August 14, 2025

Record last verified: 2025-08