Impact of Climate Change Anxiety on Sinusitis Symptoms and Quality of Life Among Adults With Chronic Rhinosinusitis: A Cross-Sectional Study

NCT07119879 | Completed DMC

• 1 other identifier: IRB00014233-17
• Study Type: observational
• Target: 134
• Locations: 1 country
• Sites: 1

Brief Summary

This cross-sectional observational study investigates the relationship between climate change anxiety and chronic rhinosinusitis (CRS) symptom severity and quality of life (QoL) in adults. As climate change continues to influence public health, individuals with chronic respiratory diseases may experience worsened symptoms due to heightened psychological stress and perceived environmental instability. The study utilizes standardized instruments including the SNOT-22 (Sino-Nasal Outcome Test), a QoL scale, and a climate change anxiety questionnaire to evaluate associations among these variables.

Conditions

Chronic Rhinosinusitis (CRS); Climate Change Anxiety; Quality of Life Impairment

Keywords

SNOT-22; psychosomatic health; environmental stress; quality of life; climate change anxiety; Chronic rhinosinusitis

Outcome Measures

Primary Outcomes (1)

• Correlation between Climate Change Anxiety and CRS Symptom Severity

  Evaluate the relationship between participants' climate change anxiety scores and their chronic rhinosinusitis symptom severity using the SNOT-22 questionnaire.

  Day 1 (Single assessment at time of survey completion)

Secondary Outcomes (1)

• Correlation between Climate Change Anxiety and Quality of Life

  Day 1 (Single assessment at time of survey completion)

Study Arms (1)

Adults with Chronic Rhinosinusitis

This cross sectional includes adult participants (≥18 years) with self-reported or physician-diagnosed chronic rhinosinusitis who completed an online questionnaire assessing climate change anxiety, SNOT-22 scores, and quality of life.

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study targets adult individuals (aged ≥18 years) residing in Egypt who have self-reported or medically diagnosed Chronic Rhinosinusitis (CRS) with symptom duration of at least 12 weeks. Participants were required to read and understand Arabic in order to complete a structured online questionnaire. Recruitment was conducted electronically through convenience sampling via social media and academic platforms.

You may qualify if:

• Participants must meet all of the following:

You may not qualify if:

• Participants will be excluded if they meet any of the following:
• Diagnosis of severe psychiatric or psychological disorders (e.g., schizophrenia, bipolar disorder) History of major chronic illnesses that may confound outcomes (e.g., cardiovascular disease, cancer, chronic neurological disease) Recent nasal or sinus surgery within the past 3 months Incomplete survey responses that prevent data analysis Participants under 18 years of age

Sponsors & Collaborators

• Sinai University: lead

Study Sites (1)

Sinai university

Cairo, 44511, Egypt

Location

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer

Study Record Dates

• First Submitted: August 6, 2025
• First Posted: August 13, 2025
• Study Start: January 1, 2025
• Primary Completion: June 25, 2025
• Study Completion: July 25, 2025
• Last Updated: August 13, 2025

Record last verified: 2025-08

Locations

EG (1)