NCT07119684

Brief Summary

Physical activity is very important for staying healthy and improving how well our brain works. Walking is a simple and easy way to exercise that can help people of all ages feel better physically and mentally. It's affordable, easy to do, and doesn't require special equipment. Walking can improve memory, thinking speed, and problem-solving skills, which are important for everyday life. This study looks at whether doing shorter walks more often (like three 10-minute walks a day) is as good for the brain as doing one longer walk (one 30-minute walk a day). This is important because many people find it hard to fit long exercise sessions into their day due to busy schedules, health issues, or personal preferences. By understanding which way of walking helps the brain the most, doctors and patients can choose exercise plans that are easier to stick to and still improve thinking skills. This study will compare these two walking routines over 6 weeks to see how they affect brain health. This clinical trial investigates the cognitive effects of two different walking exercise protocols over a 6-week period. Participants will either complete three daily 10-minute walking sessions or a single continuous 30-minute walking session. The study aims to determine whether shorter, more frequent exercise sessions provide cognitive benefits comparable to a longer, single session. Outcomes will focus on improvements in memory, processing speed, and executive function. Findings will inform recommendations for accessible and flexible exercise programs to enhance cognitive health.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
35

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2024

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 16, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 16, 2024

Completed
1.5 years until next milestone

First Submitted

Initial submission to the registry

August 6, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

August 13, 2025

Completed
Last Updated

August 13, 2025

Status Verified

August 1, 2025

Enrollment Period

2 months

First QC Date

August 6, 2025

Last Update Submit

August 6, 2025

Conditions

Keywords

Exercise Duration, Exercise Frequency, Cognitive Function, Walking Exercise

Outcome Measures

Primary Outcomes (1)

  • Change in Digit Symbol Substitution Test (DSST) Score

    Main endpoint; large effect size; reflects executive function \& speed

    Baseline and 6 weeks post-intervention

Secondary Outcomes (1)

  • Change in Stroop Test

    Baseline and 6 weeks post-intervention

Study Arms (2)

Short-Duration Walking Group

EXPERIMENTAL

Participants walked 3 sessions of 10 minutes per day, five days a week for 6 weeks, at 60% of their maximum heart rate.

Behavioral: Short-Duration Walking Exercise

Long-Duration Walking Group

ACTIVE COMPARATOR

Participants walked 1 continuous 30-minute session per day, five days a week for 6 weeks, at 60% of their maximum heart rate.

Behavioral: Long-Duration Walking Exercise

Interventions

articipants performed three 10-minute walking sessions per day, 5 days per week for 6 weeks, at 60% of their maximum heart rate on a treadmill.

Short-Duration Walking Group

Participants performed one continuous 30-minute walking session per day, 5 days per week for 6 weeks, at 60% of their maximum heart rate on a treadmill.

Long-Duration Walking Group

Eligibility Criteria

Age18 Years - 25 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Female
  • Aged between 18 and 25 years
  • Sedentary lifestyle, defined as taking \<5000 steps/day in the previous week
  • Non-smoker
  • Having a work or school schedule that allows consistent participation in the 6-week walking program
  • Able to walk on a treadmill
  • Provided written informed consent

You may not qualify if:

  • Body Mass Index (BMI) ≥ 30 kg/m²
  • Participation in another regular exercise program during the study period
  • Neurological conditions (e.g., stroke, epilepsy)
  • Severe cardiovascular conditions (e.g., heart failure, arrhythmias)
  • Any physical limitation that prevents safe walking on a treadmill
  • Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Gazi University

Ankara, Cankaya, Turkey (Türkiye)

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
Participants were not blinded (they knew their group) Investigators (those conducting and monitoring the intervention) were blinded Outcomes assessors (evaluating cognitive tests) were blinded
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: Two groups (10-minute walking group vs. 30-minute walking group) Each group receives a different intervention Participants stay in the same group throughout the study (no crossover)
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
associate professor

Study Record Dates

First Submitted

August 6, 2025

First Posted

August 13, 2025

Study Start

January 1, 2024

Primary Completion

February 16, 2024

Study Completion

February 16, 2024

Last Updated

August 13, 2025

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will share

Demographic data: age, height, weight, BMI Group assignment: 10-minute or 30-minute walking group Cognitive test scores: Stroop Test Word (STW) Stroop Test Color (STC) Stroop Test Word-Color (STWC) Digit Symbol Substitution Test (DSST) Pre- and post-intervention scores for all cognitive assessments

Shared Documents
SAP

Locations