Aortic Dissection fAlse enlarGement radIomics predictiOn

NCT07117825 | Active Not Recruiting

• 1 other identifier: 6518
• Study Type: observational
• Target: 500
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this study is to find, in acute phase of aortic dissection, CT scans characteristics through radiomics features, that can help us to predict a significant growth of dissected descending aorta or a false lumen enlargement in order to treat the patient promptly.

Conditions

Dissection; Aortic Diseases; Aortic Dissection

Outcome Measures

Primary Outcomes (1)

• Predict the false lumen enlargement (>5.5 mm aortic diameter growth at CT follow-up control) through radiomics analysis applied on CT scans.

  24 MONTHS

Interventions

AORTIC DISSECTION CT SCAN ANALYSIS OTHER

Patients with type A or type B acute aortic dissection, treated either with medical therapy or with endovascular/open surgery in the study period and who underwent subsequent radiological follow-up.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with type A or type B acute aortic dissection, treated either with medical therapy or with endovascular/open surgery in the study period and who underwent subsequent radiological follow-up.

You may qualify if:

• Patients with previous acute aortic (type A or B) dissection, undergoing medical or surgical therapy and in clinical-radiological follow-up.

You may not qualify if:

• Patients with no appropriate radiological follow up;
• Patients who died in the acute phase of aortic type A or B dissection.

Sponsors & Collaborators

• Fondazione Policlinico Universitario Agostino Gemelli IRCCS: lead

Study Sites (1)

Giovanni Tinelli

Roma, Italy

Location

MeSH Terms

Conditions

Aortic Diseases; Aortic Dissection

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases; Dissection, Blood Vessel; Aneurysm; Acute Aortic Syndrome

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Prof

Study Record Dates

• First Submitted: August 5, 2025
• First Posted: August 12, 2025
• Study Start: September 30, 2024
• Primary Completion: January 1, 2026
• Study Completion (Estimated): December 31, 2027
• Last Updated: August 12, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

IT (1)