Prevalence of Fuchs Endothelial Corneal Dystrophy in a Population of Dermatology Patients.

NCT07117071 | Completed

• 1 other identifier: IRBN1392025/CHUSTE
• Study Type: observational
• Target: 1,200
• Locations: 1 country
• Sites: 1

Brief Summary

The prevalence of Fuchs Endothelial Corneal Dystrophy (FECD) varies from 3.7 to 21.6% of adults depending on the population studied (country and age class), the method of diagnosis and the definition adopted. In the absence of available data for France, we analyzed the prevalence of Fuchs Endothelial Corneal Dystrophy (FECD) in a specific sub-population.

Conditions

Fuchs Endothelial Corneal Dystrophy

Keywords

Fuchs endothelial corneal dystrophy; specular microscopy; prevalence; carcinoma

Outcome Measures

Primary Outcomes (1)

• Dark spot in specular microscopy

  Dark sport or guttae after specular microscopy in parallel with the dermatological consultation

  Years: 1

Secondary Outcomes (3)

• Prevalence of Fuchs endothelial corneal dystrophy (FECD) as a function of age

  Years: 1

• Prevalence of Fuchs endothelial corneal dystrophy (FECD) as a function of gender

  Years: 1

• Correlation between Fuchs endothelial corneal dystrophy (FECD) and skin pathology

  Years: 1

Study Arms (1)

screening of Fuchs endothelial corneal dystrophy

Patients with screening of Fuchs endothelial corneal dystrophy will be included.

Other: collection of medical data

Interventions

collection of medical data OTHER

collection of medical data : Age, Sex, Previous cataract surgery, Cellularity, Dermatological pathology, results of screening of Fuchs endothelial corneal dystrophy by Specular microscopy

screening of Fuchs endothelial corneal dystrophy

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patient with screening of Fuchs endothelial corneal dystrophy will be included.

You may qualify if:

• Patient with screening of Fuchs endothelial corneal dystrophy

You may not qualify if:

• Patients under guardianship
• Patients unable to receive informed consent
• Patients with anterior segment pathology (declarative) (the eye concerned will not be photographed)

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Saint Etienne: lead

Study Sites (1)

CHU Saint-Etienne

Saint-Etienne, France

Location

MeSH Terms

Conditions

Fuchs' Endothelial Dystrophy; Carcinoma

Condition Hierarchy (Ancestors)

Corneal Dystrophies, Hereditary; Corneal Diseases; Eye Diseases; Eye Diseases, Hereditary; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type; Neoplasms

Study Officials

• Philippe GAIN, MD PhD

  CHU SAINT-ETIENNE

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 5, 2025
• First Posted: August 12, 2025
• Study Start: January 2, 2024
• Primary Completion: December 31, 2024
• Study Completion: December 31, 2024
• Last Updated: August 12, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)