Investigation of Test Foods With Different Hardness and Size on Lower Jaw Movements and Occlusal Morphology Which Designed With Chewing Registrations of Different Test Foods

NCT07105995 | Recruiting

• 1 other identifier: 2025/102 Rev1
• Study Type: interventional
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

One of the most important goals of prosthetic treatment is to make the occlusal morphology suitable for the patient's original anatomy. Mechanical articulators are metal devices that mimic the temporomandibular joint and lower jaw movements, and attempts have been made to make them patient-specific over the years. For this purpose, semi-adjustable articulators were first developed. Later, fully adjustable articulators were introduced to the market. Although these devices have the closest imitation mechanism to the patient's original anatomy, they have various limitations. Adjusting mechanical articulators and recording lower jaw movements have been researched in dentistry clinics and dentistry literature for many years. Due to the limitations of articulators, digital recordings of lower jaw movements have been started since 1989. Later, in 2002, the process of adjusting virtual articulators in a computer environment according to the digital recording data of the mandibular movements was started. In this way, the limitations of mechanical articulators such as metal deformation, difficulties experienced during recording, distortion of plaster and recording material, insufficient stability, adaptation problems of base plates, logistic problems between the laboratory and the physician, and inability to store data have been largely eliminated. In addition, mechanical articulators still cannot fully mimic the anatomy of the temporomandibular joint and related muscles. Digital recording of mandibular movements and transferring them to a virtual environment were first tried with electronic methods, and these systems were developed and ultrasonic and optoelectronic methods were used. Today, tooth movement records can be obtained with 3D video motion analysis methods. By superimposing these data with the data of digital models of the jaws, a mandibular movement recording method has been developed that can now produce restorations without the need for virtual or mechanical articulators. All these developments arise from the desire to record more appropriate and adaptable mandibular movement patterns, overcoming the difficulties in imitating complex patterns of mandibular movements that vary from the size, initial height and consistency of the food to the patient's mental state during the mandibular chewing movement. Thus, we will be able to obtain the most appropriate occlusal morphology for the patient to chew at maximum performance in the prosthetic or restorative procedures we will perform. With the developing technology, mandibular movement recordings can be recorded not only in the border movements as in the past, but also during chewing. In the literature, the majority of studies conducted by having the patient chew a test food are studies measuring the activity of the masticatory muscles, the distance between the incisors, the lateral movement distance or the magnitude of the chewing stroke. For this reason, in this study, mandibular movements will be recorded with optical motion tracking systems and 4-unit fixed partial dentures(FPDs) for teeth 4.4 - 4.7 will be designed according the recordings. The study will include individuals who are in the molar class 1 of the Angle classification, who have no temporomandibular joint and masticatory muscle disorders, who have no missing or extra teeth, who have no fillings or crowns on teeth numbered 4.4-4.7, who have not undergone orthodontics, and who are not allergic to the test foods. The subjects will sign a consent form. After the subjects are examined, lower and upper jaw scans and bite scans will be recorded. In the 2nd session, facebow records, border movements and chewing records with 5 different test foods will be recorded from the subjects with an optical lower jaw movement tracker(Zebris JMA Optic). These test foods were selected according to the literature and are cheese, raw carrots, boiled carrots, crispy bread and pre-polymerized silicone impression material. After recordings, fixed partial dentures will be designed via virtual articulator, border movement recordings and for 5 different foods in digital design program. 7 different FDPs designs for each subject will be overlapped with the subject's original anatomy in the Geomagic program.

Conditions

Occlusal Morphology Design With Chewing Recordings

Keywords

occlusal morphology; digital dentistry; jaw motion tracking; virtual articulator

Outcome Measures

Primary Outcomes (2)

• Linear deviation of reference points on occlusal morphology

  Following the superimposition of the designed occlusal morphologies onto the participants' original occlusal anatomy, thirteen reference points will be assessed for linear deviations measured in micrometers.

  From enrollment to data collection at 12 weeks. Occlusal morphology designs will be held on design program after data collection. Participiants do not take place at this phase of the study.

• Angular deviation of reference points on designed occlusal morphology

  Following the superimposition of the designed occlusal morphologies onto the participants' original occlusal anatomy, thirteen reference points will be assessed for angular deviations measured in micrometers."

  From enrollment to data collection at 12 weeks. Occlusal morphology designs will be held on design program after data collection. Participiants do not take place at this phase of the study.

Secondary Outcomes (2)

• Chewing cycles amplitude

  From enrollment to data collection at 12 weeks. After data collection participants do not take place on designing and analyzing phases.

• Chewing cycles width

  From enrollment to data collection at 12 weeks. Occlusal morphology designs will be held on design program after data collection. Participiants do not take place at this phase of the study.

Study Arms (1)

Data collection

EXPERIMENTAL

After enrollment of each participants data collection will be started. Data collection is the only arm of the study. This study does not have any control groups of participants. There are 7 different data collection methods. Lower jaw movements and chewing cycles of each participant will be recorded with different methods and occlusal morphologies will be designed with the data collected from each method. After that, researchers will design occlusal morphologies with collected data and overlap the designs with participants original occlusal anatomy which obtained from intraoral scans.

Other: Examination and questionnaire; Other: Intraoral scanning; Other: Facebow registrations; Other: Mandibular border movement registrations; Other: Chewing registrations

Interventions

Examination and questionnaire OTHER

Participants will be enrolled in the study and will complete the Temporomandibular Disorders/Diagnostic Criteria (TMD/DC) questionnaire. Subsequently, the investigator will conduct a clinical examination to assess each participant's eligibility based on the predefined inclusion criteria.

Data collection

Intraoral scanning OTHER

The investigator will perform intraoral scanning of the participants' maxillary and mandibular dentitions, as well as record the bite registration.

Data collection

Facebow registrations OTHER

The investigator will perform facebow registrations on the participants utilizing an optoelectronic tracking device.

Data collection

Mandibular border movement registrations OTHER

The investigator will perform mandibular border movement registrations utilizing an optoelectronic mandibular movement tracking device.

Data collection

Chewing registrations OTHER

The investigator will perform 5 chewing registrations with different test foods utilizing an optoelectronic mandibular movement tracking device.

Data collection

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• having Angle molar class 1 occlusion
• over 18 years old
• not undergone any orthodontic treatment
• not having any temporomandibular or masticatory disorders
• not having any pain or sensitivity on temporomandibular joint, masticatory muscle
• not having missing teeth or implant-supported restorations
• not having fillings or crowns on teeth 4.4 - 4.7
• not having supernumerary teeth
• not allergic to test foods
• volunteering to participate
• being a student at Istanbul University Faculty of Dentistry

You may not qualify if:

• not having Angle molar class 1 occlusion
• under 18 years old
• undergone any orthodontic treatment
• having any temporomandibular or masticatory disorders
• having any pain or sensitivity on temporomandibular joint, masticatory muscle
• having missing teeth or implant-supported restorations
• having fillings or crowns on teeth 4.4 - 4.7
• having supernumerary teeth
• allergic to test foods
• not volunteering to participate
• not being a student at Istanbul University Faculty of Dentistry

Sponsors & Collaborators

• Istanbul University: lead

Study Sites (1)

Istanbul University Department of Prosthodontics

Istanbul, Süleymaniye Fatih, 34116, Turkey (Türkiye)

RECRUITING

Related Publications (15)

• Koch GK, Gallucci GO, Lee SJ. Accuracy in the digital workflow: From data acquisition to the digitally milled cast. J Prosthet Dent. 2016 Jun;115(6):749-54. doi: 10.1016/j.prosdent.2015.12.004. Epub 2016 Jan 21.

  PMID: 26803173 BACKGROUND

• Kiseri B, Dayan SC, Yildiz M, Sulun T. The correlation between direction and amount of retrusive movement and condyle position and joint space. Cranio. 2018 Jul;36(4):250-256. doi: 10.1080/08869634.2017.1333219. Epub 2017 Jun 3.

  PMID: 28578614 BACKGROUND

• Kohyama K, Sasaki T, Hayakawa F. Characterization of food physical properties by the mastication parameters measured by electromyography of the jaw-closing muscles and mandibular kinematics in young adults. Biosci Biotechnol Biochem. 2008 Jul;72(7):1690-5. doi: 10.1271/bbb.70769. Epub 2008 Jul 7.

  PMID: 18603809 BACKGROUND

• Kohyama K, Mioche L, Bourdiol P. Influence of age and dental status on chewing behaviour studied by EMG recordings during consumption of various food samples. Gerodontology. 2003 Jul;20(1):15-23. doi: 10.1111/j.1741-2358.2003.00015.x.

  PMID: 12926747 BACKGROUND

• Strozyk P, Balchanowski J. Application of numerical simulation studies to determine dynamic loads acting on the human masticatory system during unilateral chewing of selected foods. Front Bioeng Biotechnol. 2023 May 11;11:993274. doi: 10.3389/fbioe.2023.993274. eCollection 2023.

  PMID: 37251568 BACKGROUND

• Schiffman E, Ohrbach R, Truelove E, Look J, Anderson G, Goulet JP, List T, Svensson P, Gonzalez Y, Lobbezoo F, Michelotti A, Brooks SL, Ceusters W, Drangsholt M, Ettlin D, Gaul C, Goldberg LJ, Haythornthwaite JA, Hollender L, Jensen R, John MT, De Laat A, de Leeuw R, Maixner W, van der Meulen M, Murray GM, Nixdorf DR, Palla S, Petersson A, Pionchon P, Smith B, Visscher CM, Zakrzewska J, Dworkin SF; International RDC/TMD Consortium Network, International association for Dental Research; Orofacial Pain Special Interest Group, International Association for the Study of Pain. Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for Clinical and Research Applications: recommendations of the International RDC/TMD Consortium Network* and Orofacial Pain Special Interest Groupdagger. J Oral Facial Pain Headache. 2014 Winter;28(1):6-27. doi: 10.11607/jop.1151.

  PMID: 24482784 BACKGROUND

• Bhatka R, Throckmorton GS, Wintergerst AM, Hutchins B, Buschang PH. Bolus size and unilateral chewing cycle kinematics. Arch Oral Biol. 2004 Jul;49(7):559-66. doi: 10.1016/j.archoralbio.2004.01.014.

  PMID: 15126137 BACKGROUND

• Peyron MA, Lassauzay C, Woda A. Effects of increased hardness on jaw movement and muscle activity during chewing of visco-elastic model foods. Exp Brain Res. 2002 Jan;142(1):41-51. doi: 10.1007/s00221-001-0916-5. Epub 2001 Nov 9.

  PMID: 11797083 BACKGROUND

• Cheong CW, Radomski K, Otten J, Lee SJ. A clinical comparative analysis using an optical tracking device versus conventional tracking device in the production of occlusal appliances. J Prosthodont. 2025 Apr;34(4):350-356. doi: 10.1111/jopr.13989. Epub 2024 Dec 4.

  PMID: 39632348 BACKGROUND

• Nigam AA, Lee JD, Lee SJ. A clinical comparison of sagittal condylar inclination and Bennett angle derived from a conventional electronic tracking device and an optical jaw tracking device. J Prosthet Dent. 2025 Aug;134(2):393-398. doi: 10.1016/j.prosdent.2023.10.034. Epub 2023 Nov 28.

  PMID: 38030543 BACKGROUND

• Muric A, Gokcen Rohlig B, Ongul D, Evlioglu G. Comparing the precision of reproducibility of computer-aided occlusal design to conventional methods. J Prosthodont Res. 2019 Jan;63(1):110-114. doi: 10.1016/j.jpor.2018.10.002. Epub 2018 Nov 13.

  PMID: 30446412 BACKGROUND

• Lepidi L, Galli M, Mastrangelo F, Venezia P, Joda T, Wang HL, Li J. Virtual Articulators and Virtual Mounting Procedures: Where Do We Stand? J Prosthodont. 2021 Jan;30(1):24-35. doi: 10.1111/jopr.13240. Epub 2020 Sep 2.

  PMID: 32827222 BACKGROUND

• Anderson K, Throckmorton GS, Buschang PH, Hayasaki H. The effects of bolus hardness on masticatory kinematics. J Oral Rehabil. 2002 Jul;29(7):689-96. doi: 10.1046/j.1365-2842.2002.00862.x.

  PMID: 12153460 BACKGROUND

• Shiga H, Stohler CS, Kobayashi Y. The effect of bolus size on the chewing cycle in humans. Odontology. 2001 Nov;89(1):49-53. doi: 10.1007/s10266-001-8185-0.

  PMID: 14530922 BACKGROUND

• Miyawaki S, Ohkochi N, Kawakami T, Sugimura M. Effect of food size on the movement of the mandibular first molars and condyles during deliberate unilateral mastication in humans. J Dent Res. 2000 Jul;79(7):1525-31. doi: 10.1177/00220345000790071601.

  PMID: 11005739 BACKGROUND

MeSH Terms

Interventions

Restraint, Physical; Surveys and Questionnaires

Intervention Hierarchy (Ancestors)

Behavior Control; Therapeutics; Immobilization; Investigative Techniques; Data Collection; Epidemiologic Methods; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Tonguç Sülün, PhD

  Istanbul University

  STUDY CHAIR

Central Study Contacts

AYŞENUR ÖZCAN-SEZGİN, DDS

CONTACT

+905057667873; aysenurozcan53@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 18, 2025
• First Posted: August 6, 2025
• Study Start: September 1, 2025
• Primary Completion: February 1, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: August 6, 2025

Record last verified: 2025-07

Locations

TU (1)