Beta Glucan 500 and Biological Age and Immune Age

NCT07104929 | Completed Phase 2

• 1 other identifier: BWH-002
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The primary purpose of this study is to evaluate the effects of BWH Labs - Beta Glucan 500 on biomarkers of biological and immune age among healthy adults. A single-arm, open-label prospective study will be conducted evaluating the impact of 12 weeks of supplementation with two capsules daily of Beta Glucan 500 on a variety of validated markers of biological and immune age on the comprehensive TruAge panel (TruDiagnostics, Lexington, KY).

Conditions

Aging

Keywords

aging; biological age; immunosenescence; beta glucan

Outcome Measures

Primary Outcomes (1)

• Epigenetic Testing

  Change from baseline to 12 weeks

Study Arms (1)

Beta Glucan

EXPERIMENTAL

Dietary Supplement: Beta Glucan

Interventions

Beta Glucan DIETARY_SUPPLEMENT

12 weeks of supplementation with two capsules daily of BWH Labs Beta Glucan 500

Beta Glucan

Eligibility Criteria

• Age: 40 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adult females or males age ≥ 40 years
• Ability to read and speak English
• Previous completion of a TruDiagnostic TruAge test within the past three months to enable comparison of previous biomarkers to the same biomarkers after intervention
• DunedinPACE estimate of aging \>0.9

You may not qualify if:

• Current diagnosis and treatment for an autoimmune condition
• Current use of beta-glucan or mushroom dietary supplement
• Known allergies to beta glucan, yeast, or mushrooms
• Currently pregnant or lactating women or women planning to become pregnant in the next 12 weeks
• Current diagnosis of a chronic health condition (e.g., cancer, heart failure, history of pancreatitis, type I or II diabetics on insulin) deemed clinically contraindicated for the study protocol
• Participants unable to provide consent

Sponsors & Collaborators

• OvationLab: lead

Study Sites (1)

OvationLab

Richmond, Virginia, 23220, United States

Location

MeSH Terms

Interventions

beta-Glucans

Intervention Hierarchy (Ancestors)

Glucans; Polysaccharides; Carbohydrates

Study Design

• Study Type: interventional
• Phase: phase 2
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: NETWORK
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 28, 2025
• First Posted: August 5, 2025
• Study Start: May 14, 2025
• Primary Completion: October 9, 2025
• Study Completion: October 9, 2025
• Last Updated: February 19, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)