EOIB for Laparoscopic Sleeve Gastrectomy

NCT07101835 | Completed

• 1 other identifier: EOIBLSG
• Study Type: observational
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

n obese patients, adequate pain relief in the postoperative period is a crucial parameter that affects patient comfort and hospital stay. Improving patient comfort and recovery quality can be achieved by minimizing undesirable effects such as nausea, vomiting, and inadequate analgesia. This study aimed to evaluate the impact of the external oblique intercostal block on postoperative dermatomal distribution, acute pain scores, and opioid consumption during the first 24 hours after laparoscopic sleeve gastrectomy surgery.

Conditions

Acute Pain; Regional Anesthesia; Morbid Obesity

Keywords

external oblique intercostal block; acute pain

Outcome Measures

Primary Outcomes (1)

• Extent of Sensory Blockade Measured by Cold Sensation Testing Across the Upper Abdominal Wall Following External Oblique Intercostal Block

  Participants will undergo sensory assessment using a standardized cold sensation test at 30 minutes post-block to evaluate the maximum sensory blockade. The data will be recorded as the area of sensory loss (in cm) along the anterior abdominal wall, and the results will be aggregated to report the maximum area of sensory blockade achieved with the external oblique intercostal block. Cold sensation will be categorized as Normal Cold, Reduced Cold, or No Cold Sensation. A successful block is defined as a complete loss or reduction of cold sensitivity.

  30 minutes after the blocks

Secondary Outcomes (6)

• Cumulative opioid consumption in the first 24 hours after surgery

  Postoperative Day 1

• Acute pain scores

  Postoperative Day 1

• The number of patients who required rescue analgesia

  Postoperative Day 1

• The incidences of postoperative nausea and vomiting (PONV)

  Postoperative Day 1

• The number of patients with complications

  Postoperative 7 days on an average

Study Arms (1)

Group EOIB

bilateral EOIB (60 ml, %0.25 bupivacaine, totally) + IV morphine patient-controlled analgesia (PCA)

Procedure: Bilateral ultrasound guided external oblique intercostal block (EOIB); Drug: ıv morphine PCA

Interventions

Bilateral ultrasound guided external oblique intercostal block (EOIB) PROCEDURE

Bilateral ultrasound-guided EOIB (total of 60 ml, %0.25 bupivacaine) will be performed + IV morphine PCA Patients scheduled for LSG will receive a Bilateral ultrasound guided external oblique intercostal block (EOIB) preoperatively, and sensory block status will be evaluated after 30 minutes.

Also known as: EOIB

Group EOIB

ıv morphine PCA DRUG

ıV PCA of 0,5mg/ml morphine (the bolus dose is 20 μg/kg, the lock-in time of 6-10 minutes, the 4-hour limit is adjusted to be 80% of the calculated total amount).

Also known as: morphine PCA

Group EOIB

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

patients undergoing laparoscopic sleeve gastrectomy

You may qualify if:

• years

You may not qualify if:

• Patients who did not sign the informed consent form and did not wish to participate in the study
• Patients with a history of opioid use lasting longer than four weeks
• Patients with chronic pain
• Patients with a history of allergy or hypersensitivity to local anesthetics or opioids
• Presence of severe cardiac, hepatic, or renal disease
• Patients with alcohol or drug addiction
• Conditions contraindicating the application of regional anesthesia
• Patients with severe psychiatric disorders such as psychosis or dementia that limit cooperation
• Block failure identified by dermatomal examination after the procedure
• Patients with a STOP-BANG score \> 5

Sponsors & Collaborators

• Ondokuz Mayıs University: lead

Study Sites (1)

Ondokuz Mayis University

Samsun, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Acute Pain; Obesity, Morbid

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Obesity; Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant professor

Study Record Dates

• First Submitted: July 28, 2025
• First Posted: August 3, 2025
• Study Start: August 1, 2025
• Primary Completion: November 1, 2025
• Study Completion: December 15, 2025
• Last Updated: December 23, 2025

Record last verified: 2025-12

Locations

TU (1)