Major Vascular Injuries in Elective Thoracic Surgery: A 10-Year Single-Center Experience

NCT07100509 | Completed

• 1 other identifier: B.30.2.ODM.0.20.08/ 481
• Study Type: observational
• Target: 11
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study retrospectively examines major vascular injuries that occurred during elective thoracic surgeries over a 10-year period at a single tertiary care center. Although these injuries are rare, they can lead to life-threatening complications. The study aims to determine how often these injuries happen, what causes them, and how they are managed during surgery. It also evaluates the role of preoperative imaging and planning, including cardiovascular surgery team involvement, in preventing or managing these events. The findings are intended to help improve surgical safety and guide future preventive strategies.

Conditions

Thoracic Surgery; Vascular Injury; Intraoperative Complications

Keywords

Elective Thoracic Surgery; Intraoperative Bleeding; Cardiovascular Surgery; Vascular Injury

Outcome Measures

Primary Outcomes (1)

• Incidence of Major Intraoperative Vascular Injuries During Elective Thoracic Surgeries

  The primary outcome is the incidence rate of major vascular injuries identified during elective thoracic surgeries performed between January 2015 and December 2024. Major vascular injury is defined as intraoperative bleeding from central vessels such as the subclavian artery or vein, brachiocephalic vein, innominate artery or vein, superior vena cava (SVC), or thoracic aorta, requiring immediate surgical intervention (e.g., primary repair, grafting, or ligation).

  During Surgery (Intraoperative Period)

Study Arms (1)

Patients With Intraoperative Vascular Injury

This cohort includes patients who experienced major intraoperative vascular injuries during elective thoracic surgeries between January 2015 and December 2024. All patients underwent surgical repair of the injured vessel, such as primary suturing, graft interposition, or ligation. No randomization or intervention assignment was performed. Data were collected retrospectively from medical records to evaluate patient characteristics, surgical details, transfusion requirements, preoperative imaging findings, complication rates, and clinical outcomes. No biospecimens were collected or retained.

Other: Major Vascular Injury During Elective Thoracic Surgery

Interventions

Major Vascular Injury During Elective Thoracic Surgery OTHER

This exposure refers to patients who experienced major vascular injuries during elective thoracic surgery. Injuries involved central vessels such as the subclavian artery, brachiocephalic vein, superior vena cava, and innominate vein. No experimental intervention was applied. The study retrospectively evaluated the surgical management, transfusion requirements, preoperative planning, and clinical outcomes associated with these intraoperative events.

Patients With Intraoperative Vascular Injury

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This study includes adult patients who underwent elective thoracic surgical procedures between January 2015 and December 2024 at a single tertiary care academic center. The study population is limited to patients who experienced major intraoperative vascular injuries involving central thoracic vessels such as the subclavian artery or vein, brachiocephalic vein, innominate artery or vein, superior vena cava (SVC), or thoracic aorta. All included patients required immediate surgical intervention for bleeding control. The study is retrospective and descriptive in nature.

You may qualify if:

• Patients who underwent elective thoracic surgery between January 2015 and December 2024
• Development of a major intraoperative vascular injury during surgery
• Injury involving central vessels such as the subclavian artery or vein, brachiocephalic vein, innominate artery or vein, superior vena cava (SVC), or thoracic aorta
• Availability of complete operative and postoperative medical records
• Underwent surgical repair of the vascular injury (e.g., grafting, primary repair, ligation)

You may not qualify if:

• Patients undergoing emergency thoracic surgery
• Injuries limited to pulmonary artery or its branches
• Minor bleeding from peripheral vessels that did not require major intervention
• Postoperative vascular complications (e.g., delayed hemorrhage, pseudoaneurysm)
• Missing or incomplete operative records

Sponsors & Collaborators

• Caner İşevi, MD: lead

MeSH Terms

Conditions

Vascular System Injuries; Intraoperative Complications; Blood Loss, Surgical

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases; Wounds and Injuries; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Hemorrhage

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: MD

Study Record Dates

• First Submitted: July 27, 2025
• First Posted: August 3, 2025
• Study Start: January 1, 2015
• Primary Completion: December 31, 2024
• Study Completion: December 31, 2024
• Last Updated: August 3, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will share