NCT07096245

Brief Summary

This study is testing different ways of sharing a short, community-informed video about flu and COVID-19 vaccines to see how people respond to it. The video was created with input from Indigenous community members in California and provides information to support vaccine decision-making. Participants may see the video in one of three ways: through a paid advertisement on social media, from a trusted community organization, or from someone they know personally. After watching the video, viewers will be asked to answer one question about how much they trust it, and they may choose to complete a short survey about their vaccine views and how they received the video. The goal is to understand how trust in vaccine information changes depending on who shares it, and to improve the way health messages are delivered to Indigenous and other underserved communities.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
507

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 24, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

July 31, 2025

Completed
1 month until next milestone

Study Start

First participant enrolled

September 10, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 15, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 15, 2025

Completed
Last Updated

March 6, 2026

Status Verified

March 1, 2026

Enrollment Period

3 months

First QC Date

July 24, 2025

Last Update Submit

March 4, 2026

Conditions

Keywords

vaccinationsocial mediaintervention

Outcome Measures

Primary Outcomes (2)

  • Trust in vaccine video message by dissemination arm

    Participants will be asked to answer a single poll question after viewing a 2-3 minute vaccine education video: "How much do you trust this video?" Responses will be collected on a 4-point Likert scale (Not at all, A little, Mostly, Completely). The primary outcome is the level of trust reported, compared across dissemination arms (paid social media ads, peer-to-peer sharing, and community-based organization distribution). Analysis will assess differences in trust levels based on who shared the video.

    immediately after exposure

  • Intention

    Assesses participants' reported likelihood of getting a seasonal flu or COVID-19 vaccine after viewing the intervention video. Measured on a 6-point scale from "Very unlikely" to "Very likely," including an option for participants who have already received the vaccine. Analysis will examine variation by dissemination arm and correlation with trust in the video.

    Immediately after video exposure

Secondary Outcomes (2)

  • Self-reported exposure to new information

    Immediately after video exposure

  • Trust in message source

    Immediately after video exposure

Study Arms (3)

Social media

ACTIVE COMPARATOR

Participants in this arm will view a short (2-3 minute) educational video about flu and COVID-19 vaccines through paid advertisements on Facebook and Instagram. After viewing the video, they will be asked to respond to a single poll question: "How much do you trust this video?" Participants will then be invited to complete an optional, anonymous online survey assessing vaccine confidence, trust in the information source, and willingness to share the video. All procedures are self-directed and occur online.

Behavioral: Vaccine Information Video Dissemination

Participant seed

EXPERIMENTAL

Participants in this arm are individuals who previously completed a related survey and consented to be recontacted. These "seed" participants receive a personalized video link and instructions to share it with at least 10 people in their personal networks. They will first watch the same 2-3 minute vaccine education video, answer a 1-question poll ("How much do you trust this video?"), and complete an anonymous online survey assessing vaccine attitudes, trust in the message and source, and willingness to share. Recipients of their shared video link may also complete the poll and survey. Sharing patterns are tracked via unique link analytics.

Behavioral: Vaccine Information Video Dissemination

Community based organizations

EXPERIMENTAL

Participants in this arm will view a short educational video about flu and COVID-19 vaccines distributed by trusted community-based organizations (CBOs) using their usual communication methods, such as WhatsApp, email, newsletters, or social media. After watching the video, participants will be asked to answer a 1-question poll ("How much do you trust this video?") and will be invited to complete an optional, anonymous online survey assessing vaccine attitudes, trust in the source of the information, and willingness to share the video. CBOs will use unique tracking links to monitor video engagement.

Behavioral: Vaccine Information Video Dissemination

Interventions

The intervention is a brief, community-informed educational video (2-3 minutes) focused on seasonal flu and COVID-19 vaccination. The video was developed using human-centered design and community-based participatory methods with Indigenous community members in California. It aims to promote trust in vaccines by presenting clear, culturally relevant health information. The video is disseminated using three behavioral delivery strategies: (1) paid advertisements on Facebook and Instagram targeting adults in California, (2) peer-to-peer sharing by participants who previously enrolled in the study and are invited to serve as "seeds" who share the video with their personal contacts, and (3) distribution by trusted community-based organizations (CBOs) using their existing communication networks, including WhatsApp, social media, email, and newsletters. All viewers are prompted to complete a one-question trust poll and invited to participate in an optional anonymous survey on vaccine attitud

Community based organizationsParticipant seedSocial media

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18 years or older
  • Currently resides in California
  • Able to access and view an online video
  • Able to complete an online survey in English or Spanish For Arm 2 only (Participant Seed Arm): must have participated in the prior Aim 1 survey and consented to recontact

You may not qualify if:

  • Under 18 years of age
  • Does not reside in California
  • Unable to access the internet to view the intervention video or complete the survey

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of California, San Francisco

San Francisco, California, 94158, United States

Location

Study Officials

  • Nadia Diamond-Smith, PhD, MS

    University of California, San Francisco

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 24, 2025

First Posted

July 31, 2025

Study Start

September 10, 2025

Primary Completion

December 15, 2025

Study Completion

December 15, 2025

Last Updated

March 6, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will share

We plan to share de-identified individual-level survey data collected through the optional online Qualtrics survey, including participants' self-reported trust in the video, vaccine attitudes, exposure history, sharing behavior, and demographics (e.g., age group, gender, Indigenous identification). No names, contact information, or IP addresses will be shared. Data will be available to qualified researchers upon reasonable request and subject to data use agreements that protect participant privacy.

Shared Documents
STUDY PROTOCOL, SAP, ICF

Locations