Associations Between Radiographic Inclination of Premolars and Maxillary Expansion

NCT07095374 | Enrolling By Invitation

• 1 other identifier: 2025-PREMOLARSEXPANSION
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

Recruitment of patients treated using rapid maxillary expanders with dental anchorage, with pre-treatment panoramic X-rays and post-treatment models. In the initial phase of the study, the objective is to correlate the radiographic inclination of the upper permanent premolars in the pre-treatment orthopantomography to the expansion obtained at the end of therapy using a palatal expander with dental anchorage.

Conditions

Maxillary Deficiency

Outcome Measures

Primary Outcomes (1)

• Number of required activation for maxillary expansion

  Correlation between the number of activations of the rapid palatal expander and premolar inclination (angle between the long axis of the premolars with the occlusal plane)

  T0 (pre-treatment casts/x-rays) and T1 (post-treatment casts/x-rays)

Secondary Outcomes (1)

• Canine inclination

  T0 (pre-treatment x-rays) and T1 (post-treatment x-rays)

Study Arms (1)

Orthodontic patients undergone rapid palatal expander treatment

Patients treated with rapid palatal expansion. Patients must have a pre-treatment and post-treatment orthopantomography.

Other: Rapid palatal expansion

Interventions

Rapid palatal expansion OTHER

Patients undergone orthopedic treatment with rapid palatal expander

Orthodontic patients undergone rapid palatal expander treatment

Eligibility Criteria

• Age: 6 Years - 14 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Patients referring to the Unit of Orthodontics and Pediatric Dentistry for oral care

You may qualify if:

• Patients scheduled for orthopedic treatment with rapid palatal expander
• Pre-treatment orthopantomography
• Pre and post treatment intraoral scan

You may not qualify if:

• Previous maxillofacial surgery
• cleft lip and palate
• premolar agenesis or extraction for fracture ecc.
• Previous orthopedic-orthodontic treatments

Sponsors & Collaborators

• University of Pavia: lead

Study Sites (1)

Unit of Orthodontics and Pediatric Dentistry - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Pediatrics - University of Pavia

Pavia, Lombardy, 27100, Italy

Location

MeSH Terms

Conditions

Retrognathia

Condition Hierarchy (Ancestors)

Jaw Abnormalities; Jaw Diseases; Musculoskeletal Diseases; Maxillofacial Abnormalities; Craniofacial Abnormalities; Musculoskeletal Abnormalities; Stomatognathic Diseases; Mandibular Diseases; Stomatognathic System Abnormalities; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

• Andrea Scribante, DDS, phD

  University of Pavia

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor, Principal Investigator

Study Record Dates

• First Submitted: June 26, 2025
• First Posted: July 31, 2025
• Study Start: September 1, 2025
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): July 1, 2026
• Last Updated: November 18, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

IT (1)