Saving Limbs After Cancer: Blood Vessel and Soft Tissue Reconstruction Following Sarcoma Surgery in the Legs
SARCOVASCPLAST
Immediate Vascular and Soft Tissue Reconstruction After Sarcoma Resection Involving Major Limb Vessels: Early and Midterm Outcomes From a Tertiary Center
2 other identifiers
observational
16
1 country
1
Brief Summary
This study aimed to evaluate whether immediate reconstruction of blood vessels and soft tissues can safely and effectively preserve limbs in patients undergoing surgery for sarcomas involving major arteries or veins in the arms or legs. The goal was to determine if this complex surgical approach helps avoid amputation, ensures good cancer control, and leads to acceptable complication rates and healing outcomes.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Dec 2019
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2024
CompletedFirst Submitted
Initial submission to the registry
July 15, 2025
CompletedFirst Posted
Study publicly available on registry
July 30, 2025
CompletedJuly 30, 2025
July 1, 2025
5.1 years
July 15, 2025
July 23, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
1- Limb salvage rate 2- Flap survival 3- Vascular patency
1. Limb salvage: Determined by clinical documentation of limb preservation without major amputation. 2. Flap survival: Determined by clinical evaluation of flap viability 3. Vascular patency: Determined by duplex ultrasonography or CT angiography.
At 12 months postoperatively
Study Arms (1)
STS with major vessel involvement
STS with major vessel involvement
Interventions
Eligibility Criteria
Tertiary center (sarcoma reference center), teaching hospital
You may qualify if:
- All consecutive patient presented with STS with major vessels involvement
You may not qualify if:
- All STS without major vessels involvement
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Service de Chirurgie Plastique, Reconstructrice et Esthétique, Hôpital Européen Georges Pompidou
Paris, 75, France
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Martin LHUAIRE, MD, Msc
Service de Chirurgie Plastique, Reconstructrice et Esthétique, Hôpital Européen Georges Pompidou Paris, , France 75015
- STUDY CHAIR
Laurent Lantieri, MD
Service de Chirurgie Plastique, Reconstructrice et Esthétique, Hôpital Européen Georges Pompidou Paris, , France 75015
- STUDY DIRECTOR
David BIAU, MD, PhD
Service de Chirurgie Orthopédique et oncoorthopédie, Hôpital Cochin, Paris, , France 75015
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Dr
Study Record Dates
First Submitted
July 15, 2025
First Posted
July 30, 2025
Study Start
December 1, 2019
Primary Completion
December 31, 2024
Study Completion
December 31, 2024
Last Updated
July 30, 2025
Record last verified: 2025-07
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, SAP, ICF, CSR, ANALYTIC CODE
- Time Frame
- 12 months after publication of the data
- Access Criteria
- De-identified individual participant data (IPD) and supporting documentation will be made available by the Principal Investigator upon reasonable request from qualified researchers.