BRIDGE: Blood Pressure Reduction and Intervention Delivery Via Group Engagement

NCT07091851 | Recruiting DMC

• 1 other identifier: 2025P001538
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators want to improve care for people who have had a stroke. High blood pressure is the leading cause for having a second stroke and can lead to poor brain health. The goal of this study is to compare two new ways of lowering blood pressure. The first way is to help people check their blood pressure at home. The second way is to bring people together and learn about blood pressure in a group setting. The study team thinks that using both methods together will make it easier to lower blood pressure after a stroke. The study team needs this study to test these two methods together in people who have had a stroke. The investigators believe this is an important study because having high blood pressure makes having another stroke very likely. Therefore, the investigators want to lower blood pressure in people with strokes to keep their brains as healthy as possible and to help with stroke recovery.

Conditions

Stroke; Hypertension; Home Blood Pressure Monitoring; Implementation Research

Keywords

stroke; post-stroke hypertension; implementation science

Outcome Measures

Primary Outcomes (1)

• Systolic Blood Pressure

  mean systolic blood pressure

  three months

Study Arms (1)

Control

ACTIVE COMPARATOR

Home blood pressure monitoring alone

Behavioral: Group medical visits and home blood pressure monitoring

Interventions

Group medical visits and home blood pressure monitoring BEHAVIORAL

This arm will receive instructions for home blood pressure monitoring but also be enrolled in group medical visits.

Control

Eligibility Criteria

• Age: 35 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Incident, mild to moderate, ischemic or hemorrhagic stroke (NIHSS≤15, ICH score≤3)
• history or new diagnosis of hypertension
• ability to read and speak English
• internet access
• established primary care physician at MGH

You may not qualify if:

• severe stroke (NIHSS\>15, ICH score\>3)
• discharge location to inpatient rehabilitation or skilled nursing facility
• dementia
• subjects with moderate to severe aphasia without a caregiver to consent on their behalf

Sponsors & Collaborators

• Massachusetts General Hospital: lead
• American Heart Association: collaborator

Study Sites (1)

Massachusetts General Hospital

Boston, Massachusetts, 02115, United States

RECRUITING

MeSH Terms

Conditions

Stroke; Hypertension

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Central Study Contacts

Nirupama Yechoor, MD, MSc

CONTACT

857-282-5184; nyechoor@mgh.harvard.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Instructor of Neurology

Study Record Dates

• First Submitted: July 21, 2025
• First Posted: July 29, 2025
• Study Start: September 22, 2025
• Primary Completion (Estimated): January 30, 2028
• Study Completion (Estimated): April 30, 2028
• Last Updated: September 25, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)