Long-term Survival and Influencing Factors of Patients With Pulmonary Arterial Hypertension and Diabetes

NCT07082933 | Not Yet Recruiting

• 1 other identifier: KY-20252240
• Study Type: observational
• Target: 5,000
• Locations: 0 countries
• Sites: N/A

Brief Summary

This is a multicenter retrospective cohort study on pulmonary arterial hypertension. It is expected to collect data from no less than 5,000 patients to compare the long-term overall survival of patients with and without diabetes, and analysis the risk factors of the overall survival .

Conditions

Pulmonary Arterial Hypertension (PAH)

Keywords

Pulmonary arterial hypertension; Diabetes; Mortality

Outcome Measures

Primary Outcomes (1)

• Overall Survival

  Time from diagnosis of pulmonary hypertension to death

  10 years

Secondary Outcomes (1)

• Pulmonary Artery Pressure(PAP)

  baseline

Other Outcomes (2)

• Brain natriuretic peptide

  baseline

• blood glucose

  baseline

Study Arms (2)

pulmonary arterial hypertension combined with diabetes

patients with pulmonary arterial hypertension and diabetes

Other: Standard medical treatment

pulmonary arterial hypertension without comorbid diabetes

pulmonary arterial hypertension without comorbid diabetes

Other: Standard medical treatment

Interventions

Standard medical treatment OTHER

Standard medical treatment

pulmonary arterial hypertension combined with diabetes; pulmonary arterial hypertension without comorbid diabetes

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients diagnosed with pulmonary hypertension

You may qualify if:

• Individuals aged 18 to 80 years with full capacity for civil conduct.
• Patients diagnosed with pulmonary hypertension by community-level and/or higher-level medical institutions.

You may not qualify if:

• Patients with malignant tumors.
• Other physical conditions judged by the researchers as making the patients ineligible to participate in the clinical study.

Sponsors & Collaborators

• Xijing Hospital: lead

MeSH Terms

Conditions

Pulmonary Arterial Hypertension; Diabetes Mellitus

Condition Hierarchy (Ancestors)

Hypertension, Pulmonary; Lung Diseases; Respiratory Tract Diseases; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Study Officials

• Yue Zhang, Doctor

  Department of Health Management, Xijing Hospital, Air Force Medical University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Yue Zhang, Doctor

CONTACT

0086+13022957751; zhangy718@foxmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 16, 2025
• First Posted: July 24, 2025
• Study Start: August 1, 2025
• Primary Completion (Estimated): August 1, 2027
• Study Completion (Estimated): December 31, 2027
• Last Updated: July 24, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share