Stability of Hemiparetic Patients During a Daily Complex Task

NCT07082036 | Recruiting

• 2 other identifiers: APHP2308122024-A00043-44
• Study Type: observational
• Target: 72
• Locations: 1 country
• Sites: 1

Brief Summary

Among the repercussions of hemiparesis following stroke, disturbed stability is responsible for a high risk of falls. Picking up objects from the ground, frequently trained in rehabilitation due to its risk of falling and its frequency in daily life, is a task requiring balance. To date, however, it has been little studied. We suggest that stability conditions the asymmetry adopted by patients. We hypothesise that asymmetric support at the expense of the paretic lower limb provides better stability during an unstable functional task (picking up an object from the ground) compared with the symmetrical support traditionally imposed in rehabilitation. Postural control involves stability (maintaining balance despite constraints) and orientation (posture adopted, such as the distribution of supports). Hemiparetic patients show a lack of stability and, with regard to orientation, an asymmetry in the distribution of body weight to the detriment of the paretic limb. Symmetrisation of weight distribution has been one of the predominant concepts in rehabilitation.

Conditions

Hemiparesis

Keywords

Hemiparetic patients; Stability; Orientation; Postural control; Strategy; Motion

Outcome Measures

Primary Outcomes (1)

• stability parameter: the range of the medio-lateral centre of pressure during the object picking up task

  Two forceplate platforms. 3 trials for each condition

  at baseline

Secondary Outcomes (14)

• Velocity of the centre of pressure

  at baseline

• Ellipse area of the centre of pressure

  at baseline

• Range of the centre of pressure

  at baseline

• Percentage of weight bearing

  at baseline

• Kinematics parameters

  at baseline

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Hemiparetic patients following stroke; Healthy subjects (same age, height, weight).

You may qualify if:

• All:
• Male or female ≥ 18 years
• For patients :
• Haemiparesis after a single unilateral hemispheric Stroke.
• Stroke ≥ 6 months
• Asymmetry of support between the 2 lower limbs (distribution of body weight) in a standing position at the expense of the paretic lower limb \> 10%.
• Able to stand alone, without technical aids or equipment, with feet the width of the pelvis
• Able to pick up an object from the ground alone (minimum score 3/4 item 9 of the Berg Balance Scale).
• Patient informed and having signed a consent form
• For healthy subjects:
• \- Similar characteristics (in terms of sex, age range and BMI class) to those of one of the patients already included.

Sponsors & Collaborators

• Assistance Publique - Hôpitaux de Paris: lead

Study Sites (1)

CHU Raymond Poincaré - APHP

Garches, 92380, France

RECRUITING

MeSH Terms

Conditions

Paresis; Orientation, Spatial

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Spatial Behavior; Behavior

Study Officials

• Céline Bonnyaud

  Motion Analysis Laboratory, CHU Raymond Poincaré - APHP

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Céline Bonnyaud, PhD

CONTACT

+ 33 01 71 14 49 21; celine.bonnyaud@aphp.fr

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 21, 2025
• First Posted: July 24, 2025
• Study Start: November 5, 2024
• Primary Completion (Estimated): November 1, 2026
• Study Completion (Estimated): November 1, 2026
• Last Updated: July 24, 2025

Record last verified: 2025-07

Locations

FR (1)