Transversus Abdominis Plane Block for Postoperative Pain Management in Gynaecological Cancer Surgery

NCT07077863 | Completed

• 1 other identifier: 2025-58
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to compare the efficacy of transversus abdominis plane block for postoperative analgesia in gynaecological cancer surgery. The main question(s) aimed to be answered are: \[For postoperative analgesia, a block performed by the surgeon in the area seen or a block performed by the anaesthetist before surgery?\] Patients undergoing gynaecological cancer surgery were retrospectively reviewed. The investigators evaluated the effect of a four-quadrant transversus abdominis plane block for postoperative analgesia on pain scores and postoperative opioid use.

Conditions

Peripheral Blocs

Keywords

gynecological cancer surgery; postoperative analgesia; transversus abdominis plane block

Outcome Measures

Primary Outcomes (1)

• postoperative numerical rating scale

  Our primary aim was to evaluate numerical rating scale at 24 hours postoperatively. numerical rating scale(NRS) was used to assess postoperative pain. NRS values were recorded For example, 0-10 where 0 is no pain and 10 is the worst pain imaginable.

  24 hours postoperatively

Study Arms (1)

Patients undergoing gynecologic cancer surgery

Patients undergoing transversus abominis plan block for postoperative analgesia

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients over 18 years of age who underwent surgery for gynaecological cancer between January 2024 and December 2024 and to whom we applied four quadrant transversus abdominis plane block (TAPB) from peripheral nerve blocks for postoperative analgesia were included in the stud

You may qualify if:

• \- Women aged 18 and over
• Gynaecological cancer surgery

You may not qualify if:

• \- Patients undergoing peripheral or central block in addition to transversus abdominis plane block
• Allergy or history of local anaesthetic drug allergy

Sponsors & Collaborators

• Duygu Akyol: lead

Study Sites (1)

Basaksehir Cam and Sakura City Hospital

Istanbul, Turkey (Türkiye)

Location

Related Publications (3)

• Ismail S, Siddiqui AS, Rehman A. Postoperative pain management practices and their effectiveness after major gynecological surgery: An observational study in a tertiary care hospital. J Anaesthesiol Clin Pharmacol. 2018 Oct-Dec;34(4):478-484. doi: 10.4103/joacp.JOACP_387_17.

  PMID: 30774227 BACKGROUND

• Jakobsson J, Wickerts L, Forsberg S, Ledin G. Transversus abdominal plane (TAP) block for postoperative pain management: a review. F1000Res. 2015 Nov 26;4:F1000 Faculty Rev-1359. doi: 10.12688/f1000research.7015.1. eCollection 2015.

  PMID: 26918134 BACKGROUND

• Bernard L, Lavecchia M, Trepanier G, Mah S, Pokoradi A, McGinnis JM, Alyafi M, Glezerson B, Nguyen J, Carlson V, Helpman L, Elit L, Jimenez W, Eiriksson L, Reade CJ. A double-blinded, randomized trial comparing surgeon-administered transversus abdominis plane block with placebo after midline laparotomy in gynecologic oncology surgery. Am J Obstet Gynecol. 2023 May;228(5):553.e1-553.e8. doi: 10.1016/j.ajog.2023.02.010. Epub 2023 Feb 14.

  PMID: 36791986 BACKGROUND

Study Officials

• DUYGU AKYOL, M.D

  Başakşehir Çam & Sakura City Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: July 12, 2025
• First Posted: July 22, 2025
• Study Start: January 1, 2024
• Primary Completion: December 31, 2024
• Study Completion: July 12, 2025
• Last Updated: July 23, 2025

Record last verified: 2025-07

Locations

TU (1)