Effect of Stellate Ganglion Block on Arterial Catheterization Complications in Selected Group of Patients Undergoing Elective Cardiac Surgeries

NCT07077824 | Recruiting DMC

• 1 other identifier: fmasu R156/2025
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Radial artery catheterization is the usual method for invasive monitoring in cardiac surgeries. Although it is relatively safe, complications do happen. Hematoma and ischemia are well known complications. Also, radial-to-femoral arterial pressure gradient (RFAPG) post bypass is a common event which affect management of a critical patient in a critical time. the study examines the effect of left stellate ganglion block (LSGB) on decreasing radial artery complications in cardiac surgeries

Conditions

Cardiac Surgery

Keywords

stellate ganglion block; femoral radial gradient; arterial catheterization complications

Outcome Measures

Primary Outcomes (1)

• Incidence of arterial ischemia

  Incidence of arterial ischemia in form of colour changes and confirmed by arterial duplex

  from end of surgery till hospital discharge aproximately one week

Secondary Outcomes (1)

• • Incidence of radial to femoral artery pressure gradient

  from weaning from cardiopulmonary bypass till transferal to icu aproximately 1-2 hours

Study Arms (2)

Stellate Ganglion Block group

EXPERIMENTAL

Patients will receive left stellate ganglion block US guided after induction of anesthesia and intubation and after insertion of Rt IJV CVL and before skin incision

Procedure: Stellate Ganglion Block Injection with Bupivicaine

Control group

NO INTERVENTION

Patients will undergo the surgery according to practised protocol

Interventions

Stellate Ganglion Block Injection with Bupivicaine PROCEDURE

Patients will receive left stellate ganglion block US guided after induction of anesthesia and intubation and after insertion of Rt IJV CVL and before skin incision

Stellate Ganglion Block group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Multiple procedures with expected prolonged bypass time (\>100 min)
• EF\< 35%
• Moderate or severe Pulmonary hypertension

You may not qualify if:

• Patient not willing to participate in the study.
• History of strokes / Transient ischaemic attacks
• History of Glaucoma.
• History of allergy to local anaesthetic drugs.
• Pre-existing contralateral phrenic nerve palsy.
• Patients with existing coagulopathy.
• BMI \>35

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

faculty of medicine Ain Shams University

Cairo, 02, Egypt

RECRUITING

Central Study Contacts

abdallah M soudi

CONTACT

+201111228925; Dr.soudi2014@med.asu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr.

Study Record Dates

• First Submitted: July 12, 2025
• First Posted: July 22, 2025
• Study Start: July 15, 2025
• Primary Completion: January 16, 2026
• Study Completion: March 1, 2026
• Last Updated: July 22, 2025

Record last verified: 2025-07

Locations

EG (1)