NCT07067983

Brief Summary

A Prospective Study Evaluating the Performance of the GRAPE Model in Gastric Cancer Screening and Its Detection Rates Across Different Disease Stages

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,000,000

participants targeted

Target at P75+ for all trials

Timeline
7mo left

Started May 2025

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress62%
May 2025Dec 2026

Study Start

First participant enrolled

May 30, 2025

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

July 6, 2025

Completed
10 days until next milestone

First Posted

Study publicly available on registry

July 16, 2025

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2026

Expected
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2026

Last Updated

July 16, 2025

Status Verified

July 1, 2025

Enrollment Period

1.6 years

First QC Date

July 6, 2025

Last Update Submit

July 6, 2025

Conditions

Gastric Cancer

Outcome Measures

Primary Outcomes (1)

  • GRAPE systematic screening results

    Screen-positive individuals after GRAPE systematic screening

    first visited at baseline

Interventions

Results following systematic screeningDIAGNOSTIC_TEST

The GRAPE model's output (positive or negative) determines whether patients require follow-up gastroscopy

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Individuals undergoing thoracoabdominal CT examination

You may qualify if:

  • Aged between 18 and 80 years
  • Individuals undergoing thoracoabdominal CT examination
  • Voluntarily participated in the study and provided written informed consent

You may not qualify if:

  • Patients with confirmed diagnosis of gastric cancer
  • Individuals with severe intellectual disabilities or communication disorders

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Hangzhou, Zhejiang, 310000, China

RECRUITING

MeSH Terms

Conditions

Stomach Neoplasms

Condition Hierarchy (Ancestors)

Gastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesStomach Diseases

Study Officials

  • Xiangdong Cheng

    Zhejiang Cancer Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Xiangdong Cheng

CONTACT

0086-571-881280chengxd@zjcc.org.cn

Can Hu

CONTACT

13968032995chengxd@zjcc.org.cn

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Target Duration
3 Years
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

July 6, 2025

First Posted

July 16, 2025

Study Start

May 30, 2025

Primary Completion (Estimated)

December 30, 2026

Study Completion (Estimated)

December 31, 2026

Last Updated

July 16, 2025

Record last verified: 2025-07

Data Sharing

IPD Sharing
Will not share

Locations

CN(1)