TAP Block Timing Study

NCT07064200 | Recruiting

• 1 other identifier: 25-04028793
• Study Type: interventional
• Target: 150
• Locations: 1 country
• Sites: 1

Brief Summary

This study investigates whether administering TAP blocks pre-incision provides superior postoperative pain control and reduces opioid use along with other medications compared to post-incision administration in patients undergoing elective abdominal surgeries.

Conditions

Bariatric or General Abdominal Surgeries; Bariatric Surgery Patients

Keywords

bariatric analgesia

Outcome Measures

Primary Outcomes (2)

• Mean change in opioid consumption (MME) from index procedure to 90 days post-op

  Opioid dosage quantities will be measured in morphine milligram equivalents (MME)

  Up to 90 days post-operatively

• Change in Pain Scores from index procedure on a numerical rating scale

  Patient-reported pain on a scale of 1-10.

  1, 3, 6, 24, 48, and 72 hours postoperatively

Secondary Outcomes (4)

• 1. Total Opioid Consumption in MME from Surgery to 90 Days Postoperatively

  From end of surgery to 90 days post-op.

• Patient Satisfaction Score with Postoperative Pain Management at Discharge

  At hospital discharge (within 3-5 days post-op)

• Use of Non-Opioid Analgesics within 72 Hours

  From end of surgery to 72 hours post-op

• Number of Participants with TAP Block-Related Adverse Events

  From TAP block administration to 90 days post-op.

Study Arms (2)

Pre-Incision

OTHER

TAP block administration pre-incision

Other: TAP Block

Post-Incision

OTHER

TAP block administration post-incision

Other: TAP Block

Interventions

TAP Block OTHER

the TAP block is a regional anesthesia technique that targets the somatic nerves supplying the anterior abdominal wall.

Post-Incision; Pre-Incision

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults aged between 18 and 65 years
• Scheduled for elective bariatric surgery or other elective general abdominal surgeries
• Proficient in English sufficient to understand study procedures and communicate effectively
• Capable of providing informed consent

You may not qualify if:

• Individuals under 18 years of age (minors)
• Pregnant individuals
• Prisoners
• Individuals with cognitive impairments or otherwise unable to provide informed consent independently
• Individuals with known allergies or contraindications to local anesthetics used in TAP blocks

Sponsors & Collaborators

• Weill Medical College of Cornell University: lead

Study Sites (1)

Weill Cornell Medical College - NewYork-Presbyterian Hospital

New York, New York, 10065, United States

RECRUITING

Study Officials

• Cheguevara Afaneh, MD

  Weill Medical College of Cornell University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Cheguevara Afaneh, MD

CONTACT

+1 646 962 8462; cha9043@med.cornell.edu

Hasan Ali

CONTACT

hoa4002@qatar-med.cornell.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 2, 2025
• First Posted: July 14, 2025
• Study Start: July 14, 2025
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): July 1, 2027
• Last Updated: January 27, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: beginning at 9 months and ending 36 months following article publication
• Access Criteria: Investigators whose proposed use of the data has been approved by an independent review committee (:learned intermediary:) identifies for this purpose. Proposals may be submitted up to 36 months following article publication. After 36 months the data will be available in our University's data warehouse but without the investigator support other than deposited metadata.

Locations

US (1)