Management of Multiple Adjacent Extraction Sockets

NCT07063836 | Recruiting

• 1 other identifier: 25-026
• Study Type: interventional
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

While early implant placement with guided bone regeneration (GBR) offers advantages, the desire for reduced treatment time and fewer surgical steps continues to drive the exploration of alternative approaches. In this context, the recent introduction of vestibular socket therapy (VST) presents an intriguing option. VST utilizes a minimally invasive tunnel access technique through the vestibular area to perform socket augmentation for immediate implant placement in compromised extraction sockets .

Conditions

Dental Implant in Compromised Adjacent Sockets

Keywords

dental implant, compromised socket, bone augmentation

Outcome Measures

Primary Outcomes (1)

• soft tissue stability

  it will be measured digitally using the intraoral scanner. A preoperative scanning, immediate postoperative, 3 months postoperative and 6 months postoperative scanning will be done.

  6 months after final restoration

Secondary Outcomes (1)

• buccal plate of bone regeneration

  6 months

Other Outcomes (1)

• Pink esthetic score

  6 months

Study Arms (2)

vestibular socket therapy

EXPERIMENTAL

A small incision (1 cm) is made on (vestibular area) near the base of the extracted teeth, extending slightly towards neighboring teeth. This creates a pouch for accessing the socket and surrounding bone.An immediate implant is inserted using a guide and covered with a cortical membrane

Procedure: VST

Contour augmentation and early implant placement

ACTIVE COMPARATOR

early implant placement after socket healing for four weeks using bioplug along with contour augmentation using bone and membrane

Procedure: contour augmentation and early implant placement

Interventions

VST PROCEDURE

atraumatic extraction to the hopeless teeth will be performed using periotomes followed by conventional forceps under local anesthesia.A small incision (1 cm) is made on (vestibular area) near the base of the extracted teeth, extending slightly towards neighboring teeth.Using special instruments from the VST kit, the gum tissue is carefully dissected to expose the underlying bone and an immediate implant is placed using a surgical guide. the augmentation is done using A mixture of bone chips harvested from the surgical site (autogenous bone) and a bone-grafting material (deproteinized bovine bone mineral) is used to fill any gaps and support the implant, especially in the labial bone wall (labial plate). A special 0.6 mm thick membrane is inserted through the access incision. the vestibular incision is then sutured and the provisional is inserted.

vestibular socket therapy

contour augmentation and early implant placement PROCEDURE

Teeth extraction : minimally invasive adjacent teeth extraction under anesthesia using periotome and forceps. the empty sockets will be filled with a special collagen material (BioPlug) to aid healing for 4 to 8 weeks. flap elevation : a full-thickness flap will be carefully raised using a crestal incision extended one tooth mesial and distal to the extraction location, then connected with two vertical incisions extended through the sulcus forming a trapezoid flap. Implants Insertion: The two implant is then placed into the prepared sockets using surgical guide. Bone Grafting: Any bone deficiencies are addressed by grafting. This involves placing a layer of (autogenous bone) directly on the two implants' surface, followed by a layer of a bone-grafting material (Demineralized Bone Matrix). Membrane Placement: A double-layered collagen membrane is used to cover the grafted area. Flap Closure: The previously lifted flap is repositioned and sutured back in place.

Contour augmentation and early implant placement

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• \- patients with two adjacent hopeless maxillary teeth or remaining roots in the esthetic region missing coronal tooth structure, type II socket (deficient labial plate of bone and intact overlying soft tissues), adequate palatal bone, ≥ 3 mm apical bone to engage the immediately placed implants, thereby achieving optimum primary stability (a minimum of 30 Ncm insertion torque) following teeth extraction.
• acceptable compliance and oral hygiene.

You may not qualify if:

• medically compromised patients. (Systemic diseases). general contraindication for implant placement. (Untreated periodontitis, severe bruxism , immunosuppression , uncontrolled diabetes , smokers , patients under radiation therapy, patients on bisphosphonate medications).

Sponsors & Collaborators

• British University In Egypt: lead

Study Sites (1)

The British university in Egypt

Cairo, Egypt

RECRUITING

Study Officials

• Mohamed Yousef, B.D.S

  British University In Egypt

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Mohamed G yousef, B.D.S

CONTACT

00201224289601; pgmohamed9214@bue.edu.eg

Al Hassan Diab, PhD

CONTACT

+201003642191; alhassan.diab@bue.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 3, 2025
• First Posted: July 14, 2025
• Study Start: July 14, 2025
• Primary Completion: January 1, 2026
• Study Completion: March 1, 2026
• Last Updated: August 7, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)