Fake Coughing During Bone Marrow Aspiration and Biopsy

NCT07063498 | Not Yet Recruiting

• 1 other identifier: 2024/03-04
• Study Type: interventional
• Target: 80
• Locations: 0 countries
• Sites: N/A

Brief Summary

Hematology patients go through many difficult periods during the diagnosis process. One of the most commonly used methods in the diagnosis of hematological diseases is bone marrow aspiration and biopsy (BMAB). BMAB is an invasive procedure and may cause pain in patients. For this purpose, a local anesthetic agent is used during the procedure. However, no effective method has been developed to prevent pain in patients. Both pharmacological and non-pharmacological methods are used to manage pain. Among non-pharmacological methods, cognitive distraction techniques such as feigned coughing and stress balls are used to reduce pain and stress. Some studies have reported that "fake coughing" reduces pain during procedures that cause temporary, sharp pain, such as parenteral injections or venipuncture. A literature review revealed that patients undergoing bone marrow aspiration and biopsy experience intense stress and pain, but there are insufficient studies examining these concepts. This study is expected to contribute to the nursing literature. The aim of this study is to determine the effect of fake coughing and stress ball application on pain during bone marrow aspiration and biopsy.

Conditions

Bone Marrow Aspiration and Biopsy; Pain; Feigned Cough; Stress Ball

Keywords

bone marrow aspiration and biopsy; Pain; Stress

Outcome Measures

Primary Outcomes (1)

• Pain Intensity During Bone Marrow Aspiration and Biopsy

  Patient-reported pain intensity during bone marrow aspiration and biopsy procedures measured by a 10-point Visual Analog Scale (VAS), where 0 = no pain and 10 = worst pain imaginable.

  Immediately after the procedure.

Study Arms (3)

Cough Group

EXPERIMENTAL

Voluntary Coughing Maneuver

Behavioral: Coughing Maneuver

control phase

NO INTERVENTION

Patients undergo biopsy without any additional intervention.

Stress Ball Group

EXPERIMENTAL

Stress Ball Intervention

Behavioral: Stress ball

Interventions

Coughing Maneuver BEHAVIORAL

1\. Voluntary Coughing Maneuver (Hileli Öksürük): Patients in this group were instructed to perform a voluntary coughing maneuver immediately prior to the percutaneous biopsy procedure. The maneuver was demonstrated by the clinician, and patients were asked to perform 2-3 forceful coughs while in the biopsy position, 30 seconds before needle insertion, to reduce anxiety and procedural pain perception.

Cough Group

Stress ball BEHAVIORAL

2\. Stress Ball Intervention: Patients were given a standard-sized rubber stress ball to hold and repeatedly squeeze during the entire percutaneous biopsy procedure. The intervention began 1 minute before needle insertion and continued until the procedure was completed. The aim was to provide a behavioral distraction to alleviate anxiety and pain.

Stress Ball Group

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosed with cancer at least 3 months ago
• Over 18 years of age
• Able to communicate adequately
• No psychiatric problems
• Willing to participate in the study

You may not qualify if:

• Patients with communication problems
• Patients with psychiatric problems

Sponsors & Collaborators

• Firat University: lead

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Gül DURAL, PhD

CONTACT

+904242370000; gulkaya@firat.edu.tr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD

Study Record Dates

• First Submitted: July 3, 2025
• First Posted: July 14, 2025
• Study Start: January 22, 2026
• Primary Completion (Estimated): August 1, 2026
• Study Completion (Estimated): September 20, 2026
• Last Updated: January 23, 2026

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share