Chronic Mouth Breathing and SARS-CoV-2 Positivity in the Pediatric Population

NCT07063134 | Completed

• 1 other identifier: DEUORTO-CMB-2025
• Study Type: observational
• Target: 173
• Locations: 1 country
• Sites: 1

Brief Summary

Numerous non-scientific articles on the internet assert the significance of nasal breathing in protecting against COVID-19. Although nasal breathing is anticipated to result in a reduced intake of bioparticles when compared to mouth breathing due to the filtering mechanisms present in the nasal cavity, we have yet to identify any in vivo studies within the literature that definitively ascertain the correlation between mouth breathing and COVID-19 positivity. Consequently, this study aimed to investigate the impact of chronic mouth breathing on testing positive for COVID-19 in children.

Conditions

SARS-CoV-2 Infection

Keywords

Coronavirus- Mouth breathing - Nasal breathing - Delta variant

Outcome Measures

Primary Outcomes (1)

• Rate of COVID-19 Positivity in Chronic Mouth Breathers Compared to Nasal Breathers

  Proportion of COVID-19 positivity among chronic mouth breathers compared to nasal breathers

  At 2 weeks post-COVID-19 recovery"

Study Arms (2)

COVID-19 Positive Group

Participants who tested positive for SARS-CoV-2 by PCR at the time of evaluation.

COVID-19 Negative Group

Participants who tested negative for SARS-CoV-2 by PCR at the time of evaluation.

Eligibility Criteria

• Age: 10 Hours - 18 Hours
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

A total of 173 patients aged between 10 and 17 years, without any systemic diseases or COVID-19 vaccinations, who were undergoing COVID-19 testing, were included in the study.

You may qualify if:

• tested for COVID-19

You may not qualify if:

• Not tested for COVID-19

Sponsors & Collaborators

• Dokuz Eylul University: lead

Study Sites (1)

Usak University Faculty of Dentistry

Izmir, Turkey (Türkiye)

Location

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: OTHER
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Orthodontics

Study Record Dates

• First Submitted: June 26, 2025
• First Posted: July 14, 2025
• Study Start: March 2, 2022
• Primary Completion: March 5, 2022
• Study Completion: May 2, 2022
• Last Updated: July 14, 2025

Record last verified: 2025-06

Locations

TU (1)